New softer cement could reduce repeat spine fractures

NCT ID NCT05676320

Ongoing Disease control Sponsor: Inossia AB Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two bone cements used to treat painful spinal fractures caused by osteoporosis. One cement includes a softener (V-Flex) to make it less rigid, while the other is standard cement (V-Steady). The goal is to see if the softer cement reduces the chance of new fractures nearby and improves pain and function. About 200 participants with one recent fracture will be followed for two years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: bone cement with cement softener (Inossia® Cement Softener)
What this could lead to: If it works, this could provide a safer, more effective option for treating spinal fractures, potentially reducing the risk of new fractures nearby.
What could go wrong: This is a mid-stage trial with 203 participants, so results may not apply to everyone. Adding a softener might not improve outcomes and could introduce unknown risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoporosis spinal fracture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

VERTEBRAL COMPRESSION FRACTURE

Contacts and locations

Locations

Beam Radiology

Calgary, Alberta, Canada
Clínico San Carlos

Madrid, Spain
Fundación Jiménez Díaz

Madrid, Spain
Hopsital Medina del Campo

Medina del Campo, Spain
Hospital in Mechernich

Mechernich, Germany
Lodz University Hospital

Lodz, Poland
Mannheim University Hospital

Mannheim, Germany
Puerta de Hierro

Madrid, Spain
University Hospital in Valladolid

Valladolid, Spain

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