New softer cement could reduce repeat spine fractures
NCT ID NCT05676320
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two bone cements used to treat painful spinal fractures caused by osteoporosis. One cement includes a softener (V-Flex) to make it less rigid, while the other is standard cement (V-Steady). The goal is to see if the softer cement reduces the chance of new fractures nearby and improves pain and function. About 200 participants with one recent fracture will be followed for two years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bone cement with cement softener (Inossia® Cement Softener)
What this could lead to
If it works, this could provide a safer, more effective option for treating spinal fractures, potentially reducing the risk of new fractures nearby.
What could go wrong
This is a mid-stage trial with 203 participants, so results may not apply to everyone. Adding a softener might not improve outcomes and could introduce unknown risks.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Beam Radiology
Calgary, Alberta, Canada
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Clínico San Carlos
Madrid, Spain
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Fundación Jiménez Díaz
Madrid, Spain
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Hopsital Medina del Campo
Medina del Campo, Spain
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Hospital in Mechernich
Mechernich, Germany
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Lodz University Hospital
Lodz, Poland
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Mannheim University Hospital
Mannheim, Germany
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Puerta de Hierro
Madrid, Spain
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University Hospital in Valladolid
Valladolid, Spain