New hope for pancreatic cancer: drug combo trial launches

NCT ID NCT07255404

Recruiting now Disease control Sponsor: BioNTech SE Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 29, 2026 · Updated 2 times

Summary

This study tests a new drug called BNT327 combined with standard chemotherapy in adults with metastatic pancreatic cancer that has not been treated before. The goal is to see if the combination shrinks tumors better than chemo alone. About 105 participants will be enrolled, and researchers will monitor side effects and how long any response lasts.

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Conditions

The condition(s) this trial relates to.

pancreatic ductal adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PANCREATIC DUCTAL ADENOCARCINOMA (PDAC)

Contacts and locations

Locations

Flinder's Medical Centre
NOT_YET_RECRUITING

Bedford Park, 5042, Australia
Fudan University Shanghai Cancer Center
RECRUITING

Shanghai, 201318, China
GenesisCare
RECRUITING

Saint Leonards, 2065, Australia
Henan Cancer Hospital
RECRUITING

Zhengzhou, 450008, China
Huashan Hospital, Fudan University
RECRUITING

Shanghai, 200040, China
Jilin Cancer Hospital
NOT_YET_RECRUITING

Changchun, 130012, China
One Clinical Research
NOT_YET_RECRUITING

Mount Pleasant, 6153, Australia
Peninsula & South Eastern Haematology and Oncology Group
RECRUITING

Frankston, 3199, Australia
Pindara Private Hospital
NOT_YET_RECRUITING

Benowa, 4217, Australia
Shandong University Cancer Hospital
NOT_YET_RECRUITING

Jinan, 250117, China
Sichuan Cancer Hospital
RECRUITING

Chengdu, 610041, China
St Vincent's Hospital
NOT_YET_RECRUITING

Melbourne, 3065, Australia
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
RECRUITING

Guangzhou, 510000, China
Sunshine Coast Private Hospital
NOT_YET_RECRUITING

Sunshine Coast, 4575, Australia
The Affiliated Cancer Hospital of Guangxi Medical University
RECRUITING

Nanning, 530200, China
The Alfred Hospital
NOT_YET_RECRUITING

Melbourne, 3004, Australia
The First Affiliated Hospital of China Medical University
RECRUITING

Shenyang, 110001, China
The First Affiliated Hospital of Nanchang University
RECRUITING

Nanchang, 330052, China
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
RECRUITING

Wuhan, 430030, China
Tsinghua Changgung Hospital
RECRUITING

Beijing, 102218, China
Westmead Hospital
NOT_YET_RECRUITING

Sydney, 2145, Australia
Yunnan Cancer Hospital
RECRUITING

Kunming, 650118, China
Zhejiang Provincial People's Hospital
RECRUITING

Hangzhou, 325200, China
Zhongshan Hospital Affiliated with Dalian University
NOT_YET_RECRUITING

Dalian, 116001, China

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