New drug combo shows promise in shrinking advanced lung tumors

NCT ID NCT06892548

Recruiting now Disease control Sponsor: BioNTech SE Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 28 times

Summary

This study tests two experimental drugs, BNT324 and BNT327, together in people with advanced lung cancer that has spread or come back. The goal is to see if the combination can shrink tumors and control the disease. About 594 adults with small cell or non-small cell lung cancer will take part. The study is currently recruiting.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Adana City Hospital
RECRUITING

Adana, 01230, Turkey (Türkiye)
Ankara City Hospital
RECRUITING

Ankara, 06800, Turkey (Türkiye)
Barwon Health
RECRUITING

Geelong, Victoria, 3220, Australia
Beijing Cancer Hospital
RECRUITING

Beijing, Beijing Municipality, 100142, China
Beijing GoBroad Hospital
RECRUITING

Beijing, Beijing Municipality, 102200, China
Bendigo Hospital
RECRUITING

Bendigo, Victoria, 3550, Australia
Bristol Haematology and Oncology Centre
RECRUITING

Bristol, BS2 8ED, United Kingdom
Cedars Sinai Medical Center
RECRUITING

Los Angeles, California, 90048, United States
Chris O'Brien Lifehouse
RECRUITING

Camperdown, New South Wales, 2050, Australia
Cleveland Clinic Taussig Cancer Institute Case Comprehensive Cancer Center
RECRUITING

Cleveland, Ohio, 44195, United States
Dr. Abdurrahman Yurtaslan Oncology Teaching and Research Hospital
RECRUITING

Ankara, 06105, Turkey (Türkiye)
First Affiliated Hospital, Zhejiang University School of Medicine
RECRUITING

Hangzhou, Zhejiang, 310003, China
Fujian Medical University Union Hospital
RECRUITING

Fuzhou, Fujian, 350001, China
Guangxi Medical University Cancer Hospital
RECRUITING

Nanning, Guangxi Zhuang, 530021, China
Hacettepe University Medical Faculty
RECRUITING

Ankara, 06100, Turkey (Türkiye)
Henan Provincial Cancer Hospital
RECRUITING

Zhengzhou, Henan, 450003, China
Icahn School of Medicine at Mount Sinai PRIME
RECRUITING

New York, New York, 10029, United States
Jilin Cancer Hospital
RECRUITING

Changchun, Jilin, 130000, China
Jinan Central Hospital
RECRUITING

Jinan, Shandong, 250013, China
Jingzhou First People's Hospital
RECRUITING

Jingzhou, Hubei, 434000, China
John Theurer Cancer Center at Hackensack UMC
RECRUITING

Hackensack, New Jersey, 07601, United States
Kaohsiung Medical University Chung-Ho Memorial Hospital
RECRUITING

Kaohsiung City, 807, Taiwan
Koc University Hospital
RECRUITING

Istanbul, 34010, Turkey (Türkiye)
Linyi Cancer Hospital
RECRUITING

Shandong, Linyi, 276001, China
MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
Mayo Clinic Arizona
RECRUITING

Phoenix, Arizona, 13400, United States
Mayo Clinic in Florida
RECRUITING

Jacksonville, Florida, 32224, United States
Mayo Clinic-Rochester
RECRUITING

Rochester, Minnesota, 55905, United States
Memorial Sloan Kettering Cancer Center (MSKCC)
RECRUITING

New York, New York, 10021, United States
Nanjing Chest Hospital
RECRUITING

Nanjing, Jiangsu, 210029, China
National Cheng Kung University Hospital
RECRUITING

Tainan, 704, Taiwan
Precision NextGen Oncology and Research Center
RECRUITING

Beverly Hills, California, 90212, United States
Sakarya Training and Research Hospital
RECRUITING

Sakarya, 54187, Turkey (Türkiye)
Shandong Cancer Hospital
RECRUITING

Jinan, Shandong, 250117, China
Shanghai GoBroad Cancer Hospital
RECRUITING

Shanghai, Shanghai Municipality, 200125, China
Sir Run Run Shaw Hospital, Zhejiang University, School of Medicine
RECRUITING

Hangzhou, Zhejiang, 310016, China
St George's Hospitals NHS Foundation Trust
RECRUITING

London, SW170QT, United Kingdom
St John of God Subiaco Hospital
RECRUITING

Subiaco, Western Australia, 6008, Australia
St. James's University Hospital
RECRUITING

Leeds, LS97TF, United Kingdom
Sunshine Hospital
RECRUITING

Saint Albans, Victoria, 3021, Australia
Taichung Veterans General Hospital
RECRUITING

Taichung, 40705, Taiwan
Taipei Veterans General Hospital
RECRUITING

Taipei, 11217, Taiwan
Texas Oncology - DFW
RECRUITING

Dallas, Texas, 75246, United States
Texas Oncology - Northeast
RECRUITING

Tyler, Texas, 75702, United States
The Christie NHS Foundation Trust
RECRUITING

Manchester, M204BX, United Kingdom
The First Affiliated Hospital of Nanchang University
RECRUITING

Nanchang, Jiangxi, 330209, China
The First Affiliated Hospital of Xian Jiaotong University
RECRUITING

Xi'an, Shaanxi, 710061, China
The First Affiliated Hospital of Xinxiang Medical University
RECRUITING

Weihui, Henan, 453100, China
The Second Affiliated Hospital of Nanchang University
RECRUITING

Nanchang, Jiangxi, 330006, China
UCLA - David Geffen School of Medicine
RECRUITING

Santa Monica, California, 90404, United States
University College London Hospital
RECRUITING

London, W1T 7HA, United Kingdom
University of Iowa Hospitals & Clinics PARENT
RECRUITING

Iowa City, Iowa, 52242, United States
Virginia Cancer Specialists
RECRUITING

Fairfax, Virginia, 22031, United States
West China Hospital, Sichuan University
RECRUITING

Chengdu, Sichuan, 611100, China
Xiangyang Central Hospital
RECRUITING

Xiangyang, Hubei, 441021, China
Yeditepe University Medical School Hospital
RECRUITING

Istanbul, 31755, Turkey (Türkiye)
Yichang Central People's Hospital
RECRUITING

Yichang, Hubei, 443000, China
Zhejiang Cancer Hospital
RECRUITING

Hangzhou, Zhejiang, 310022, China

Conditions

Explore the condition pages connected to this study.

ADVANCED LUNG CANCER