New immune combo takes on tough colorectal cancer
NCT ID NCT07079631
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 27 times
Summary
This study tests a new drug (BNT314) designed to help the immune system attack cancer, combined with another immune-boosting drug (BNT327) and chemotherapy. It is for people with advanced colorectal cancer that did not respond well to initial treatment or, in one part, for those who have not yet had any treatment. The goal is to see if the combination is safe and can shrink tumors or slow cancer growth.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Asklepios Tumorzentrum Hamburg
RECRUITINGHamburg, 22763, Germany
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Centro Integral Oncologico Clara Campal
RECRUITINGMadrid, 28050, Spain
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Christie NHS Foundation
RECRUITINGManchester, M20 4BX, United Kingdom
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Cleveland Clinic Taussig Cancer Institute Case Comprehensive Cancer Center
RECRUITINGCleveland, Ohio, 44195, United States
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Guy's & St Thomas' NHS Foundation Trust, Guy's Hospital
RECRUITINGLondon, SE19RT, United Kingdom
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Hospital HM Nou Delfos
RECRUITINGBarcelona, 08023, Spain
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Hämatologisch-Onkologische Praxis Eppendorf - HOPE
RECRUITINGHamburg, 20249, Germany
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National Cancer Center Hospital
RECRUITINGChūōku, 104-0045, Japan
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National Cancer Center Hospital East
RECRUITINGKashiwa, 277-8577, Japan
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START Midwest
RECRUITINGGrand Rapids, Michigan, 49546, United States
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The Royal Marsden NHS
RECRUITINGSutton, SM2 5PT, United Kingdom
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The University of Texas MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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Vall D'Hebrón Hospital
RECRUITINGBarcelona, 08035, Spain
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Yale University
RECRUITINGNew Haven, Connecticut, 06511, United States
Conditions
Explore the condition pages connected to this study.