BioNTech tests new cancer drug targeting specific tumor marker

NCT ID NCT05262530

Summary

This early-phase study tested a new drug called BNT142 in people with advanced solid tumors that have a specific marker called CLDN6. The main goals were to find a safe dose and see if the drug showed any signs of helping shrink tumors. The trial included patients with cancers like ovarian, lung, and testicular cancer who had already tried other standard treatments.

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Contacts and locations

Locations

  • Cambridge University Hospitals NHS Foundation Trust

    Cambridge, CB2 0QQ, United Kingdom

  • Churchill Hospital - Oxford University Hospitals NHS Foundation Trust

    Oxford, OX3 7LE, United Kingdom

  • Duke University Medical Center

    Durham, North Carolina, 27705, United States

  • HM Nou Delfos General Hospital

    Barcelona, 08023, Spain

  • Hammersmith Hospital, Imperial College School Of Medicine - Imperial College Healthcare NHS Trust

    London, W12 0HS, United Kingdom

  • Hospital Universitario 12 de Octubre - Centro de Actividades Ambulatorias

    Madrid, 28041, Spain

  • Hospital Universitario Vall D'Hebron

    Barcelona, 08035, Spain

  • Hospital Universitario Virgen de la Victoria Campus Universitario de Teatinos

    Málaga, 29010, Spain

  • MD Anderson Cancer Center

    Madrid, 28033, Spain

  • NEXT Virginia

    Fairfax, Virginia, 22031, United States

  • National University Cancer Institute - National University Hospital

    Singapore, 119074, Singapore

  • START Madrid CIOCC Hospital Universitario HM Sanchinarro

    Madrid, 28050, Spain

  • START Madrid-FJD Hospital Universitario Fundacion Jimenez Diaz

    Madrid, 28040, Spain

  • South Texas Accelerated Research Therapeutics (START) - San Antonio

    San Antonio, Texas, 78229, United States

  • The Clatterbridge Cancer Centre NHS Foundation Trust

    Liverpool, L7 8YA, United Kingdom

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • University of Maryland Medical Center

    Baltimore, Maryland, 21201, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.