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New combo therapy shows promise for aggressive lung cancer

NCT ID NCT04702880

Completed Disease control Sponsor: Bristol-Myers Squibb Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding an experimental drug (BMS-986012) to standard chemotherapy and immunotherapy could help people with advanced small cell lung cancer live longer without their cancer growing. The trial involved 135 newly diagnosed patients. Researchers measured safety and how well the treatment worked compared to standard care alone.

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Conditions

The condition(s) this trial relates to.

small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EXTENSIVE-STAGE SMALL-CELL LUNG CANCER

Contacts and locations

Locations

  • Local Institution

    Cincinnati, Ohio, 45267, United States

  • Local Institution

    Dallas, Texas, 75390, United States

  • Local Institution - 0001

    Malvern, Victoria, 3144, Australia

  • Local Institution - 0002

    Durham, North Carolina, 27710, United States

  • Local Institution - 0003

    Westmead, New South Wales, 2145, Australia

  • Local Institution - 0004

    Murdoch, Western Australia, 6150, Australia

  • Local Institution - 0005

    Majadahonda, 28222, Spain

  • Local Institution - 0006

    Málaga, 29010, Spain

  • Local Institution - 0007

    Barcelona, Barcelona [Barcelona], 08035, Spain

  • Local Institution - 0012

    Edmonton, Alberta, T6G 1Z2, Canada

  • Local Institution - 0021

    Madrid, 28041, Spain

  • Local Institution - 0022

    Hackensack, New Jersey, 07601, United States

  • Local Institution - 0023

    Greenslopes, Queensland, 4120, Australia

  • Local Institution - 0029

    Rozzano, 20089, Italy

  • Local Institution - 0030

    Peschiera del Garda, 37019, Italy

  • Local Institution - 0031

    Pisa, 56124, Italy

  • Local Institution - 0034

    Ghent, 9000, Belgium

  • Local Institution - 0036

    Athens, 11527, Greece

  • Local Institution - 0038

    Athens, 185 47, Greece

  • Local Institution - 0039

    Amsterdam, North Holland, 1081 HV, Netherlands

  • Local Institution - 0040

    Groningen, 9700RB, Netherlands

  • Local Institution - 0041

    Craiova, 200542, Romania

  • Local Institution - 0042

    Cluj-Napoca, 400015, Romania

  • Local Institution - 0043

    Bucharest, 022328, Romania

  • Local Institution - 0045

    Heraklion, Irakleío, 715 00, Greece

  • Local Institution - 0048

    Lodz, 93-338, Poland

  • Local Institution - 0049

    Gdansk, 80-214, Poland

  • Local Institution - 0050

    Liège, 4000, Belgium

  • Local Institution - 0051

    Charleroi, Hainaut, 6060, Belgium

  • Local Institution - 0060

    Cincinnati, Ohio, 45267, United States

  • Local Institution - 0064

    Brampton, Ontario, L6R 3J7, Canada

  • Local Institution - 0066

    Arnhem, 6815 AD, Netherlands

  • Local Institution - 0067

    Cleveland, Ohio, 44106-1716, United States

  • Local Institution - 0069

    Takatsuki, Osaka, 5698686, Japan

  • Local Institution - 0070

    Ōsaka-sayama, Osaka, 589-8511, Japan

  • Local Institution - 0073

    Sendai, Miyagi, 980-0873, Japan

  • Local Institution - 0075

    Birmingham, Alabama, 35249, United States

  • Local Institution - 0077

    Ina-machi, Saitama, 362-0806, Japan

  • Local Institution - 0081

    Nashville, Tennessee, 37203, United States

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