New triple therapy shows promise for stubborn high blood pressure in seniors

NCT ID NCT06041529

First seen Feb 19, 2026 · Last updated May 08, 2026 · Updated 15 times

Summary

This study tests whether a new three-drug combination (telmisartan, amlodipine, and chlorthalidone) works better than another three-drug combo (telmisartan, amlodipine, and hydrochlorothiazide) for elderly patients whose blood pressure remains high despite taking two drugs. About 198 people aged 65 and older with essential hypertension will take one of the two combinations for up to 26 weeks. The main goal is to see which combo lowers nighttime blood pressure more effectively and safely.

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Contacts and locations

Locations

  • Chonnam National University Hospital

    Gwangju, 61469, South Korea

  • Gwangju Veterans Hospital

    Gwangju, 62284, South Korea

  • Hanyang university medical center

    Seoul, 04763, South Korea

  • Korea University Guro Hospital

    Seoul, 08308, South Korea

  • Pusan National University Yangsan Hospital

    Busan, 50612, South Korea

  • Seoul national University Budang hospital

    Seoul, 13620, South Korea

  • The Catholic University of Korea Bucheon St.Mary's Hospital

    Seoul, Gyeonggi-do, 14647, South Korea

  • The Catholic University of Korea Daejeon ST. Mary's Hospital

    Daejeon, 34943, South Korea

  • The Catholic University of Korea, Eunpyeong St. Mary's Hospital

    Seoul, 03312, South Korea

  • The Catholic University of Korea, Incheon ST. Mary's Hospital

    Incheon, 21431, South Korea

  • The Catholic University of Korea, ST. Vincent's Hospital

    Gyeonggi-do, 16247, South Korea

  • The Catholic University of Korea, Seoul ST. Mary's Hospital

    Seoul, 06591, South Korea

  • The Catholic University of Korea, Uijeongbu ST. Mary's Hospital

    Seoul, 11765, South Korea

  • The Catholic University of Korea, Yeouido ST. Mary's Hospital

    Seoul, 07345, South Korea

  • Wonju Severance Christian Hospital

    Wŏnju, Gangwon-do, 26426, South Korea

Conditions

Explore the condition pages connected to this study.