New Triple-Drug combo aims to lower blood pressure better in seniors

NCT ID NCT06041529

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new fixed-dose combination pill containing three blood pressure medicines (telmisartan, amlodipine, and chlorthalidone) against another triple combination (with hydrochlorothiazide instead of chlorthalidone) in elderly patients whose blood pressure is not well controlled. About 198 participants aged 65 and older will take one of the two combinations for up to 26 weeks. The main goal is to see which pill better lowers nighttime blood pressure, with safety monitored throughout.

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Conditions

The condition(s) this trial relates to.

essential hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chonnam National University Hospital

    Gwangju, 61469, South Korea

  • Gwangju Veterans Hospital

    Gwangju, 62284, South Korea

  • Hanyang university medical center

    Seoul, 04763, South Korea

  • Korea University Guro Hospital

    Seoul, 08308, South Korea

  • Pusan National University Yangsan Hospital

    Busan, 50612, South Korea

  • Seoul national University Budang hospital

    Seoul, 13620, South Korea

  • The Catholic University of Korea Bucheon St.Mary's Hospital

    Seoul, Gyeonggi-do, 14647, South Korea

  • The Catholic University of Korea Daejeon ST. Mary's Hospital

    Daejeon, 34943, South Korea

  • The Catholic University of Korea, Eunpyeong St. Mary's Hospital

    Seoul, 03312, South Korea

  • The Catholic University of Korea, Incheon ST. Mary's Hospital

    Incheon, 21431, South Korea

  • The Catholic University of Korea, ST. Vincent's Hospital

    Gyeonggi-do, 16247, South Korea

  • The Catholic University of Korea, Seoul ST. Mary's Hospital

    Seoul, 06591, South Korea

  • The Catholic University of Korea, Uijeongbu ST. Mary's Hospital

    Seoul, 11765, South Korea

  • The Catholic University of Korea, Yeouido ST. Mary's Hospital

    Seoul, 07345, South Korea

  • Wonju Severance Christian Hospital

    Wŏnju, Gangwon-do, 26426, South Korea