Leukemia drug given as a shot shows promise in early trial

NCT ID NCT07222579

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a drug called blinatumomab, given as a shot under the skin, for adults with a rare type of leukemia called mixed phenotype acute leukemia (MPAL). The trial includes three groups: newly diagnosed patients who cannot have strong chemo, patients in remission but with leftover cancer cells, and patients whose cancer came back or didn't respond to treatment. The goal is to see if the drug can help achieve remission or clear remaining cancer cells.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

blinatumomab (Blincyto®)

What this could lead to

If successful, this could offer a new treatment option for adults with a rare and hard-to-treat leukemia, potentially leading to remission without intensive chemotherapy.

What could go wrong

This is an early-phase trial with only 78 participants, so results may not apply to all patients. The drug may cause side effects like neurological problems or infections, and not everyone may respond.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute biphenotypic leukemia mixed phenotype acute leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • West Virginia University Cancer Institute

    RECRUITING

    Morgantown, West Virginia, 26506, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••