New eye ointment aimed at soothing chronic eyelid inflammation

NCT ID NCT06400511

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a medicated ointment called pimecrolimus 0.3% for people with blepharitis, a condition that causes red, irritated eyelids. The trial planned to include 477 participants aged 2 and older, applying the ointment twice daily to the eyelid margins. The main goal was to see if it could clear eyelid debris and reduce discomfort. However, the study was terminated early, so final results are not available.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
pimecrolimus 0.3% ophthalmic ointment
What this could lead to
If successful, this could provide a new treatment option for blepharitis, reducing eyelid debris and discomfort.
What could go wrong
The study was terminated, so results are incomplete. It is unclear if the ointment works better than placebo, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Clinical Investigative Site

    Pheonix, Arizona, 85032, United States

  • Clinical Investigator Site

    Garden Grove, California, 92843, United States

  • Clinical Investigator Site

    Glendale, California, 91204, United States

  • Clinical Investigator Site

    Inglewood, California, 90301, United States

  • Clinical Investigator Site

    Newport Beach, California, 92663, United States

  • Clinical Investigator Site

    Petaluma, California, 94954, United States

  • Clinical Investigator Site

    Rancho Cordova, California, 95670, United States

  • Clinical Investigator Site

    Aurora, Colorado, 80045, United States

  • Clinical Investigator Site

    Crystal River, Florida, 34429, United States

  • Clinical Investigator Site

    Largo, Florida, 33773, United States

  • Clinical Investigator Site

    Tampa, Florida, 33603, United States

  • Clinical Investigator Site

    Atlanta, Georgia, 30339, United States

  • Clinical Investigator Site

    Morrow, Georgia, 30260, United States

  • Clinical Investigator Site

    Pittsburg, Kansas, 66762, United States

  • Clinical Investigator Site

    Louisville, Kentucky, 40206, United States

  • Clinical Investigator Site

    Havre de Grace, Maryland, 21078, United States

  • Clinical Investigator Site

    Medina, Minnesota, 55340, United States

  • Clinical Investigator Site

    Kansas City, Missouri, 64154, United States

  • Clinical Investigator Site

    Washington, Missouri, 63090, United States

  • Clinical Investigator Site

    Garner, North Carolina, 27529, United States

  • Clinical Investigator Site

    Cincinnati, Ohio, 45242, United States

  • Clinical Investigator Site

    Cranberry Township, Pennsylvania, 16066, United States

  • Clinical Investigator Site

    Smyrna, Tennessee, 37167, United States

  • Clinical Investigator Site

    Austin, Texas, 78731, United States

  • Clinical Investigator Site

    Lakeway, Texas, 78738, United States

  • Clinical Investigator Site

    San Antonio, Texas, 78229, United States

  • Clinical Investigator Site

    Clinton, Utah, 84015, United States

  • Clinical Investigator Site

    Lynchburg, Virginia, 24502, United States

  • Investigative Site

    St Louis, Missouri, 63131, United States

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