New bladder cancer treatment tested before surgery

NCT ID NCT04919512

Ongoing Disease control Sponsor: Janssen Research & Development, LLC Source: ClinicalTrials.gov ↗

Summary

This study is testing two experimental drug approaches for people with muscle-invasive bladder cancer who are scheduled to have their bladder removed. One approach uses a drug-releasing device placed in the bladder plus an IV immunotherapy drug. The other uses just the IV drug alone. The goal is to see if these treatments can shrink or eliminate the cancer before surgery, potentially improving outcomes for patients who cannot receive standard chemotherapy.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

ASL Napoli 2 Nord-SM delle Grazie Hospital

Pozzuoli, 80078, Italy
AZ Sint Jan Brugge Oostende AV

Bruges, 8000, Belgium
Agaplesion Frankfurter Diakonie Kliniken GmbH, Markus Krankenhaus

Frankfurt am Main, 60431, Germany
Algemeen Ziekenhuis Sint-Jan

Bruges, 8310, Belgium
Arkansas Urology

Little Rock, Arkansas, 72211, United States
Associated Medical Professionals

Syracuse, New York, 13210, United States
Azienda Ospedaliera Universitaria Citta della Salute e della Scienza di Torino

Torino, 10126, Italy
Azienda Ospedaliero Universitaria Pisana

Pisa, 56126, Italy
Baptist Hospital of Miami

Miami, Florida, 33176, United States
Barts Health NHS Trust

London, EC1A 7BE, United Kingdom
Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States
CHU Montpellier

Montpellier, 34295, France
CHU Nimes

Nîmes, 30029, France
Canisius-Wilhelmina Ziekenhuis

Nijmegen, 6532SZ, Netherlands
Carmel Medical Center

Haifa, 3436212, Israel
Carolina Urologic Research Center

Myrtle Beach, South Carolina, 29572, United States
Centre Interuniversitaire Ambroise Pare - Ambroise Paré

Mons, 7000, Belgium
City of Hope

Duarte, California, 91010, United States
Clinica Univ. de Navarra

Madrid, 28027, Spain
Clinical La Croix Du Sud - Ramsay Santé

Quint-Fonsegrives, 31130, France
Clinique Pasteur

Toulouse, 31076, France
Clinique Tivoli Ducos

Bordeaux, 33000, France
Colorodo Urology- St. Anthony Hospital

Golden, Colorado, 80401, United States
David C. Pratt Cancer Center

St Louis, Missouri, 63141, United States
DuPage Medical Group

Lisle, Illinois, 60532, United States
Ellis Fischel Cancer Center

Columbia, Missouri, 65201, United States
First Urology

Jeffersonville, Indiana, 47130, United States
Fund. Puigvert

Barcelona, 08041, Spain
Gangnam Severance Hospital

Seoul, 06273, South Korea
Genesis Research

San Diego, California, 92123, United States
HIA se Sainte-Anne - Toulon

Toulon, 83041, France
Hadassah Medical Center

Jerusalem, 91120, Israel
Haga ziekenhuis

The Hague, 2545 AA, Netherlands
Hopital Bichat Claude Bernard

Paris, 75877, France
Hopital Europeen Georges-Pompidou

Paris, 75015, France
Hopital Henri Mondor

Créteil, 94000, France
Hopital de Jolimont

Haine Saint Paul La Louviere, 7100, Belgium
Hopital de la Timone

Marseille, 13005, France
Hosp Univ A Coruna

A Coruña, 15006, Spain
Hosp Virgen de La Victoria

Málaga, 29010, Spain
Hosp. Univ. Marques de Valdecilla

Santander, 39002, Spain
Hosp. Univ. San Cecilio

Granada, 18016, Spain
Hospices Civils de Lyon HCL

Pierre-Bénite, 69495, France
Hospital Universitario 12 de Octubre

Madrid, 28041, Spain
Houston Metro Urology

Houston, Texas, 77027, United States
Huntsman Cancer Institute

Salt Lake City, Utah, 84112, United States
Hôpital Privé Le Bois

Lille, 59000, France
ICH Hopital A. Morvan

Brest, 29200, France
IRCCS Istituto Clinico Humanitas

Rozzano, 20089, Italy
IRCCS Ospedale San Raffaele

Milan, 20132, Italy
Inje University Haeundae Paik Hospital

Busan, 612-030, South Korea
Istituto Dei Tumori Di Milano

Milan, 20133, Italy
Istituto Europeo di Oncologia

Milan, 20141, Italy
Istituto Nazionale Tumori Fondazione G. Pascale

Naples, 80131, Italy
Istituto Nazionale Tumori Regina Elena

Roma, 00144, Italy
Keimyung University Dongsan Hospital

Daegu, 42601, South Korea
Korea University Anam Hospital

Seoul, 02841, South Korea
Kyungpook National University Chilgok Hospital

Daegu, 41404, South Korea
Lancashire Teaching Hospitals NHS Foundation Trust Royal Preston Hospital

Preston, PR2 9HT, United Kingdom
Marien hospital Herne

Herne, 44625, Germany
Mayo Clinic

Jacksonville, Florida, 32224, United States
Mayo Clinic 1

Rochester, Minnesota, 55905, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Michigan Institute of Urology, PC

Troy, Michigan, 48084, United States
MidLantic Urology

Bala-Cynwyd, Pennsylvania, 19004, United States
Montefiore Medical Center

The Bronx, New York, 10467, United States
Mount Sinai Queens Infusion Center

Astoria, New York, 11102, United States
National Cancer Center

Goyang-si, 10408, South Korea
New York University Langone Medical Center

New York, New York, 10017, United States
Ospedale Civile Ramazzini

Carpi, 41012, Italy
Ospedale San Giuseppe Moscati di Avellino

Avellino, 83100, Italy
Penn Medicine - PerelmanCenter for Advanced Medicine

Baltimore, Maryland, 21218, United States
Polyclinique de Limoges - Francois Chenieux

Limoges, 87000, France
Pusan National University Yangsan Hospital

Yangsan, 50612, South Korea
Rabin Medical Center - Hasharon Hospital

Petah Tikva, 49372, Israel
Radboud Umcn

Nijmegen, 6525 GA, Netherlands
Rambam Health Care Campus

Haifa, 3109601, Israel
Robert Wood Johnson University Hospital

New Brunswick, New Jersey, 08901, United States
SPDC Villa Scassi

Genova, 16100, Italy
SUNY Upstate Medical University

Syracuse, New York, 13202, United States
Samsung Medical Center

Gangnam Gu, 06351, South Korea
Seoul National University Hospital

Seoul, 03080, South Korea
Severance Hospital

Seoul, 03722, South Korea
Staedtisches Klinikum Braunschweig

Braunschweig, 38118, Germany
Tel Aviv Sourasky Medical Center

Tel Aviv, 6423906, Israel
The Catholic University of Korea Seoul St Mary s Hospital

Seoul, 06591, South Korea
The Chaim Sheba Medical Center

Ramat Gan, 52621, Israel
The Ohio State University

Columbus, Ohio, 43210, United States
UAMS Winthrop P. Rockefeller Cancer Institute

Little Rock, Arkansas, 72205, United States
Universitaetsklinikum Halle Saale

Halle, 06120, Germany
Universitatsklinikum Munster

Münster, 48149, Germany
University Of Maryland Medical Center

Baltimore, Maryland, 21201, United States
University Of Minnesota

Minneapolis, Minnesota, 55455, United States
University Of Pittsburgh Medical Center UPMC Hillman Cancer Center

Pittsburgh, Pennsylvania, 15232, United States
University of Alabama at Birmingham

Birmingham, Alabama, 35294, United States
University of Florida Health Jacksonville

Jacksonville, Florida, 32209, United States
University of Louisville - James Graham Brown Cancer Center

Louisville, Kentucky, 40202, United States
University of Washington School of Medicine

Seattle, Washington, 98195, United States
Urological Associates of Southern Arizona, P.C.

Tucson, Arizona, 85741, United States
Urology Associates

Nashville, Tennessee, 37209, United States
Urology San Antonio Research

San Antonio, Texas, 78229, United States
Urology of Indiana

Indianapolis, Indiana, 46260, United States
Vivantes Klinikum Am Urban

Kreuzberg, 10967, Germany
Wake Forest University Baptist Medical Center (WFUBMC) - Comprehensive Cancer Center

Winston-Salem, North Carolina, 27103, United States
Washington University School Of Medicine - Center For Advanced Medicine (CAM)

St Louis, Missouri, 63110-1010, United States
Winship Cancer Institute Emory University

Atlanta, Georgia, 30322, United States
ZNA Jan Palfijn

Merksem, 2170, Belgium
Ziekenhuis Oost-Limburg

Genk, 3600, Belgium
Ziekenhuisgroep Twente

Almelo, 7600, Netherlands

Conditions

Explore the condition pages connected to this study.

URINARY BLADDER NEOPLASMS