New drug cocktail may let bladder cancer patients keep their bladder

NCT ID NCT06809140

First seen Jan 05, 2026 · Last updated May 16, 2026 · Updated 18 times

Summary

This study tests whether a combination of two drugs (enfortumab vedotin and pembrolizumab) can shrink muscle-invasive bladder cancer enough to avoid bladder removal surgery. About 47 adults with stage T2-3 bladder cancer will receive the drugs for several months. If the cancer disappears completely, they continue on maintenance drugs; if not, they undergo standard cystectomy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • City of Hope

    RECRUITING

    Duarte, California, 91010, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Columbia University Irving Medical Center

    RECRUITING

    New York, New York, 10032, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fox Chase Cancer Center

    RECRUITING

    Philadelphia, Pennsylvania, 19111, United States

    Contact Email: •••••@•••••

    Contact

  • Icahn School of Medicine at Mount Sinai

    RECRUITING

    New York, New York, 10029, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Indiana University Melvin and Bren Simon Comprehensive Cancer Center

    RECRUITING

    Indianapolis, Indiana, 46202, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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