New hope for stomach cancer: targeted drug BL-M07D1 enters final trial

NCT ID NCT07152405

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tests a new drug called BL-M07D1 against standard chemotherapy in 490 people with HER2-positive advanced stomach or gastroesophageal junction cancer that has worsened after initial treatment. The study aims to see if BL-M07D1 helps people live longer or slows cancer growth. Participants will receive either BL-M07D1 or a doctor-chosen chemotherapy, given by infusion every few weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

BL-M07D1 (an antibody-drug conjugate targeting HER2)

What this could lead to

If successful, this could offer a new treatment option for people with HER2-positive advanced stomach cancer whose current therapy has stopped working.

What could go wrong

This is a phase 3 trial, but the drug is still experimental. It may not improve survival or could have side effects like other chemotherapies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gastric adenocarcinoma gastroesophageal junction adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fudan University Shanghai Cancer Center

    RECRUITING

    Shanghai, Shanghai Municipality, China

    Contact

  • Harbin Medical University Cancer Hospital

    RECRUITING

    Harbin, Heilongjiang, China

    Contact