New drug BL-B01D1 enters human trials for Hard-to-Treat cancers

NCT ID NCT05194982

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tests a new drug called BL-B01D1 in people with advanced solid tumors that have not responded to standard treatments. The study has two parts: first, to find a safe dose, and second, to check how well that dose works and how the body handles it. About 570 participants will take part to help determine if this drug is worth studying further.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

BL-B01D1 (a drug given by IV infusion)

What this could lead to

If it works, this could point toward a new treatment option for people with advanced solid tumors that have not responded to standard therapies.

What could go wrong

This is an early Phase 1 trial focused on safety and dosing, so it is too soon to know if the drug will be effective. Side effects are possible and will be closely monitored.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Head and Neck Neoplasms Neoplasm Metastasis non-small cell lung carcinoma small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chongqing University Cancer Hospital

    RECRUITING

    Chongqing, Chongqing Municipality, China

    Contact

  • Hunan Cancer Hospital

    RECRUITING

    Changsha, Hunan, China

    Contact

  • Renmin Hospital of Wuhan University

    RECRUITING

    Wuhan, Hubei, China

    Contact

  • Shanghai Oriental Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, China

    Contact

  • Shanxi Cancer Hospital

    RECRUITING

    Taiyuan, Shanxi, China

    Contact

  • Sun Yat-sen University Cancer Center

    RECRUITING

    Guangzhou, Guangdong, 510060, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Second Affiliated Hospital of Guangzhou Medical University

    RECRUITING

    Guangzhou, Guangdong, China

    Contact

  • Union Hospital Tongji Medical College, Huazhong University of Science and Technology

    RECRUITING

    Wuhan, Hubei, China

    Contact