Experimental drug BIVV020 shows promise in rare blood disorder

NCT ID NCT04269551

First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 26 times

Summary

This early-stage study tested a single dose of an experimental drug called BIVV020 in 12 adults with cold agglutinin disease, a rare condition where the immune system attacks red blood cells. The main goal was to check safety and how well the drug is tolerated. Researchers also looked at whether the drug reduces red blood cell breakdown and how it affects the immune system's complement pathway.

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Contacts and locations

Locations

  • Investigational Site Number :2760001

    Essen, 45147, Germany

  • Investigational Site Number :3800001

    Milan, Milano, 20122, Italy

  • Investigational Site Number :5280001

    Amsterdam, 1105AZ, Netherlands

  • Investigational Site Number :5780001

    Bergen, 5021, Norway

  • Investigational Site Number :8260001

    London, London, City of, NW1 2PJ, United Kingdom

  • Investigational Site Number :8400002

    Fayetteville, Georgia, 30214, United States

  • Investigational Site Number :8400004

    Seattle, Washington, 98108, United States

  • Investigational Site Number :8400006

    The Bronx, New York, 10467, United States

  • Investigational Site Number :8400008

    Pittsburgh, Pennsylvania, 15232, United States

  • Investigational Site Number :8400009

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.