Cancer-killing virus injected into spinal fluid to fight advanced lung cancer

NCT ID NCT07264569

First seen Jan 04, 2026 · Last updated May 15, 2026 · Updated 20 times

Summary

This early-stage study tests a new treatment called BioTTT001, a virus designed to attack cancer cells, in people with advanced non-small cell lung cancer that has spread to the lining of the brain and spinal cord (meningeal metastasis). About 42 adults aged 18-70 who have not responded to standard treatments will receive the virus through a special port in the head. The main goals are to check safety, find the best dose, and see if it helps control the disease.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Phase Ib/II Clinical Study to Evaluate the Safety, Tolerability, Biodistribution Characteristics and Preliminary Efficacy of Recombinant Human nsIL12 Oncolytic Adenovirus Injection (BioTTT001) in the Treatment of Patients With Recurrent/Progressive Non-s

    RECRUITING

    Zhengzhou, Henan, 450000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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