BioNTech tests new cancer drugs in first human trial

NCT ID NCT04710043

Summary

This was the first-ever study in people to test the safety and early effects of two new cancer drugs, BNT152 and BNT153, developed by BioNTech. It involved 86 adults with advanced solid tumors that had spread or could not be removed by surgery, and for whom standard treatments were no longer working. The main goal was to find safe dose levels and see how the drugs behaved in the body, while also checking for any early signs that the drugs might help shrink tumors.

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Contacts and locations

Locations

  • Duke Cancer Center

    Durham, North Carolina, 27710, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Masaryk Memorial Cancer Institute

    Brno, 65653, Czechia

  • NEXT Oncology

    San Antonio, Texas, 78229, United States

  • Robert H. Lurie Comprehensive Cancer Center, Northwestern University

    Chicago, Illinois, 60611, United States

  • Sarah Cannon Research Institute at Tennessee Oncology

    Nashville, Tennessee, 37203, United States

  • Yale Cancer Center

    New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.