New drug trial aims to slow kidney damage in IgA nephropathy patients

NCT ID NCT05852938

Ongoing Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This study is testing whether the drug BION-1301 can help adults with IgA nephropathy, a kidney disease that can lead to kidney failure. About 383 participants will receive either the drug or a placebo injection every two weeks for two years. The main goal is to see if the drug reduces protein in the urine, a key sign of kidney damage, and slows the decline in kidney function.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Capital District Renal Physicians

Clifton Park, New York, 12065, United States
Cleveland Clinic-9500 Euclid Ave

Cleveland, Ohio, 44109-1900, United States
Columbia Nephrology Associates , P.A. - Columbia

Columbia, South Carolina, 29203-6476, United States
DaVita Clinical Research

El Paso, Texas, 79925, United States
Dallas Renal Group - 1411 N Beckley Ave

Dallas, Texas, 75230, United States
Dallas Renal Group - Waxachie - 2460 N. I-35

Dallas, Texas, 75237-3461, United States
Denver Nephrology Research Division

Denver, Colorado, 80230-6441, United States
East Texas Nephrology Associates

Lufkin, Texas, 75904-3132, United States
Icahn School of Medicine at Mount Sinai

New York, New York, 10029-6504, United States
Intermed Consultants

Edina, Minnesota, 55435-2129, United States
Knoxville Kidney Center, PLLC - Frenova F1

Knoxville, Tennessee, 37923, United States
Nephrology Associales of Northern Illinois and Indiana

Hinsdale, Illinois, 60521-3640, United States
Nephrology Associates PC - Flushing

Flushing, New York, 11355-5045, United States
Nephrology Associates of Northern Illinois and Indiana - 7836 W Jefferson Blvd

Fort Wayne, Indiana, 46804, United States
Nephrology Associates of Northern Virginia-8501 Arlington Blvd

Fairfax, Virginia, 22033-1907, United States
Nephrology Consultants, LLC

Huntsville, Alabama, 35805-4104, United States
NorthShore University HealthSystem

Evanston, Illinois, 60201-1700, United States
Northeast Clinical Research Center, LLC

Bethlehem, Pennsylvania, 18017-2159, United States
Novartis Investigative Site

La Plata, Buenos Aires, B1902COS, Argentina
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Catamarca, Catamarca Province, K4700, Argentina
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Barracas, Ciudad Autónoma de BuenosAires, C1280AEB, Argentina
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Rosario, Santa Fe Province, S2013DTC, Argentina
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Santa Fe, Santa Fe Province, S3000EPV, Argentina
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Buenos Aires, C1425, Argentina
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Gosford, New South Wales, 2250, Australia
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Kogarah, New South Wales, 2217, Australia
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Liverpool, New South Wales, 2170, Australia
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Penrith, New South Wales, 2750, Australia
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St Leonards, New South Wales, 2065, Australia
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Cairns North, Queensland, 4870, Australia
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Box Hill, Victoria, 3128, Australia
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St Albans, Victoria, 3021, Australia
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Bonheiden, Antwerpen, 2820, Belgium
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Ghent, Oost-Vlaanderen, 9000, Belgium
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Roeselare, West-Vlaanderen, 8800, Belgium
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Liège, Liège, Belgium
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Lodelinsart, 6042, Belgium
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Woluwe-Saint-Lambert, 1200, Belgium
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Santana, Amapá, 68925-000, Brazil
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Belo Horizonte, Minas Gerais, 30130-100, Brazil
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Maringá, Paraná, 87013-040, Brazil
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Porto Alegre, Rio Grande do Sul, 90035-074, Brazil
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Joinville, Santa Catarina, 89227-680, Brazil
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São Bernardo do Campo, São Paulo, 09780-000, Brazil
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São Paulo, São Paulo, 01323-001, Brazil
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São Paulo, 04023-900, Brazil
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Vancouver, British Columbia, V5Z 1M9, Canada
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Brampton, Ontario, L6Z 4N5, Canada
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East York, Ontario, M4C 5T2, Canada
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London, Ontario, N6A 5A5, Canada
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Toronto, Ontario, M5G 2N2, Canada
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Greenfield Park, Quebec, J4V 2H1, Canada
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Montreal, Quebec, H1T 2M4, Canada
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Hefei, Anhui, 230601, China
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Beijing, Beijing Municipality, 100034, China
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Foshan, Guangdong, 528000, China
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Guangzhou, Guangdong, 510080, China
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Guangzhou, Guangdong, 510280, China
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Shenzhen, Guangdong, 518036, China
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Nanning, Guangxi, 530021, China
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Guiyang, Guizhou, 550002, China
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Wuhan, Hubei, 430060, China
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Nanjing, Jiangsu, 210029, China
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Nantong, Jiangsu, 226001, China
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Wuxi, Jiangsu, 214023, China
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Nanchang, Jiangxi, 330006, China
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Jinan, Shandong, 250021, China
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Qingdao, Shandong, 266005, China
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Shanghai, Shanghai Municipality, 200040, China
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Taiyuan, Shanxi, 030001, China
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Taiyuan, Shanxi, 650000, China
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Chengdu, Sichuan, 610072, China
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Ürümqi, Xinjiang, 830001, China
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Wulumuji, Xinjiang, 830054, China
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Hangzhou, Zhejiang, 310009, China
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Taizhou, Zhejiang, 317000, China
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Zagreb, City of Zagreb, 10000, Croatia
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Biškupec Zelinski, 10380, Croatia
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Rijeka, 51000, Croatia
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Vinkovci, 32100, Croatia
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Prague, Praha, Hlavní Mesto, 128 08, Czechia
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Nîmes, Gard, 30029, France
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Lille, Nord, 59000, France
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Lyon, Rhône, 69437, France
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Grenoble, 38043, France
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Paris, 75010, France
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Paris, 75015, France
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Augsburg, Bavaria, 86156, Germany
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Hanover, Lower Saxony, 30459, Germany
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Hanover, Lower Saxony, 30625, Germany
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Mainz, Rhineland-Palatinate, 55131, Germany
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Trier, Rhineland-Palatinate, 54292, Germany
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Magdeburg, Saxony-Anhalt, 39120, Germany
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Jena, Thuringia, 07747, Germany
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Essen, 45147, Germany
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Pátrai, Achaïa, 265 04, Greece
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Athens, Attica, 12462, Greece
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Kalamaria, Thessaloniki, 551 34, Greece
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Heralkion, 71409, Greece
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Ioannina, 450 01, Greece
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Ioannina, 455 00, Greece
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Thessaloniki, 546 29, Greece
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Hyderabad, Andhra Pradesh, 500084, India
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Chandigarh, Chandigarh, 160012, India
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Faridabad, Haryana, 121002, India
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Bengaluru, Karnataka, 560004, India
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Trivandrum, Kerala, 695011, India
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Jaipur, Rajasthan, 302001, India
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Jaipur, Rajasthan, 302017, India
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Vellore, Tamil Nadu, 632004, India
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Lucknow, Uttar Pradesh, 226005, India
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Kolkata, West Bengal, 700014, India
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Dehradun, 248001, India
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Beersheba, Southern District, 84101, Israel
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Holon, Tel Aviv, 58000, Israel
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Ramat Gan, Tel Aviv, 52394, Israel
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Be’er Ya‘aqov, 70300, Israel
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Ramat Gan, 5262100, Israel
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Tel Aviv, 64239, Israel
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Bari, Apulia, 70124, Italy
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Foggia, Apulia, 71100, Italy
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Naples, Campania, 80131, Italy
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Modena, Emilia-Romagna, 41124, Italy
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Trieste, Friuli Venezia Giulia, 34149, Italy
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Pavia, Lombardy, 27100, Italy
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Ranica, Lombardy, 24020, Italy
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Kasugai-Shi, Aiti, 486-0804, Japan
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Toyoake-shi, Aiti, 470-1192, Japan
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Urayasu-Shi, Chiba, 279-0021, Japan
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Sapporo, Hokkaidô, 060-8604, Japan
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Kitakyushu, Hukuoka, 802-8555, Japan
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Yokohama, Kanagawa, 236-0004, Japan
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Kashihara, Nara, 634-8522, Japan
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Nara, Nara, 630-8581, Japan
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Osaka, Osaka, 558-0056, Japan
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Bunkyo-Ku, Tokyo, 113-8431, Japan
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Hachioji-Shi, Tokyo, 192-0071, Japan
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Minato-Ku, Tokyo, 105-8471, Japan
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Shinjuku-Ku, Tokyo, 162-0054, Japan
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Chiba, 260-8712, Japan
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Niigata, 951-8520, Japan
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Okayama, 700-8558, Japan
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Tokyo, 105-8470, Japan
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Yufu-Shi, Ôita, 879-5503, Japan
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Kuantan, Pahang, 25100, Malaysia
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Sibu, Sarawak, 96000, Malaysia
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Kajang, Selangor, 43000, Malaysia
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Kuala Lumpur, WilayahPersekutuan KualaLumpur, 50586, Malaysia
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Kuala Lumpur, WilayahPersekutuan KualaLumpur, 59100, Malaysia
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Chihuahua, Chiapas, 31217, Mexico
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Barrio Belisario Domínguez Secc, Mexico City, 14080, Mexico
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Oaxaca, Mexico City, 68000, Mexico
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Aguascalientes, 20259, Mexico
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Chihuahua City, 64060, Mexico
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Monterrey, 64060, Mexico
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Dongan-Gu, Anyang-Si, Gyeonggido, 14068, South Korea
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Guri-si, Gyeonggido, South Korea
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Uijeongbu-si, Gyeonggido, 11765, South Korea
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Jongno-gu, Seoul Teugbyeolsi, 03080, South Korea
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Seodaemun-gu, Seoul Teugbyeolsi, 03722, South Korea
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Seongbuk-Gu, Seoul Teugbyeolsi, 02841, South Korea
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Cheonan, South Korea
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Daejeon, 301721, South Korea
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Seoul, 06973, South Korea
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Manises, Valencia, 46940, Spain
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Barcelona, 8035, Spain
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Girona, 17007, Spain
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Lleida, 25198, Spain
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Lugo, 27880, Spain
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Madrid, 28007, Spain
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Madrid, 28041, Spain
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Seville, 41009, Spain
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Keelung, Keelung, 204, Taiwan
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Changhua County, 50006, Taiwan
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Hsinchu, Taiwan
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Hualien City, 970, Taiwan
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Kaohsiung City, Taiwan
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Tainan, 704, Taiwan
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Taipei, 100, Taiwan
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Taipei, 116, Taiwan
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Bornova, İzmir, 35100, Turkey (Türkiye)
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İzmit, Kocaeli, 41380, Turkey (Türkiye)
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Antalya, 07070, Turkey (Türkiye)
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Kayseri, 38039, Turkey (Türkiye)
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Bristol, Bristol, City of, BS10 5NB, United Kingdom
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Brighton, East Sussex, BN2 5BE, United Kingdom
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Salford, Lancashire, M6 8HD, United Kingdom
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Leicester, Leicestershire, LE5 4PW, United Kingdom
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London, London, City of, SE5 9RS, United Kingdom
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Nottingham, Nottinghamshire, NG5 1PB, United Kingdom
OHSU - Oregon Clinical and Translational Research Institute

Portland, Oregon, 97239, United States
Swedish Center for Comprehensive Care

Seattle, Washington, 98104, United States
University Of Iowa Hospitals And Clinics

Iowa City, Iowa, 52242-1009, United States
University of Alabama at Birmingham: The Kirklin Clinic

Birmingham, Alabama, 35233-1926, United States
University of California, San Francisco

San Francisco, California, 94143, United States
University of Cincinnati College of Medicine - 231 Albert Sabin Way

Cincinnati, Ohio, 45267-2827, United States
University of Colorado Hospital

Aurora, Colorado, 80045, United States
University of Texas MD Anderson Cancer Center-1155 Pressler

Houston, Texas, 77030-2348, United States
Valiance Clinical Research

South Gate, California, 90280-5219, United States
Vida Medical Centers - Pembroke Pines

Pembroke Pines, Florida, 33023-2213, United States

Conditions

Explore the condition pages connected to this study.

IGA NEPHROPATHY IMMUNOGLOBULIN A NEPHROPATHY