Generic antifungal drug shows promise in early comparison study

NCT ID NCT06983665

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared a new generic version of liposomal amphotericin B (an antifungal drug) to the brand-name version (AmBisome®) in 58 healthy Chinese adults. Each volunteer received a single dose of both drugs at different times to see if the generic works the same way in the body. The goal was to check bioequivalence, meaning the generic should release the same amount of drug into the bloodstream. Safety was also monitored. This is a key step toward offering a more affordable treatment option for serious fungal infections.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Liposomal amphotericin B

What this could lead to

If successful, this could lead to a more affordable generic version of an important antifungal drug.

What could go wrong

This is a small, early-stage bioequivalence study in healthy people, not patients. It does not test effectiveness against infections, so the generic may still fail in real-world use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Febrile Neutropenia Invasive Fungal Infections systemic mycosis visceral leishmaniasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Jinan Central Hospital, No.105, Jiefang Road,

    Jinan, Shandong, China