New combo tackles tough pancreatic cancer in early trial

NCT ID NCT04132505

First seen Nov 03, 2025 · Last updated May 14, 2026 · Updated 26 times

Summary

This early-phase trial tested two drugs—binimetinib and hydroxychloroquine—in 34 people with advanced pancreatic cancer that has a KRAS gene mutation. The goal was to find the safest dose and see if the combination could slow tumor growth. Participants had already tried at least one other treatment. The study is complete, and results help guide future research.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.