New hope for rare leukemia patients who can't use standard targeted therapy

NCT ID NCT04322383

First seen Apr 08, 2026 · Last updated May 16, 2026 · Updated 7 times

Summary

This study tests a drug called binimetinib in people with hairy cell leukemia that does not have the BRAF gene mutation. Standard treatments don't work for these patients. The drug targets a different gene (MEK) that is often active in this type of leukemia. About 40 adults will take the drug twice daily in 28-day cycles to see if it can shrink or control their cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.