New hope for painful hand and foot pustules: phase 3 trial launches
NCT ID NCT07219420
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 3 trial tests whether the drug bimekizumab can clear or nearly clear the pustules and skin lesions of palmoplantar pustulosis (PPP) on the hands and feet. About 320 adults with moderate to severe PPP will receive either bimekizumab or a placebo for 16 weeks, with an option to continue on the drug afterward. The main goal is to see how many achieve clear or almost clear skin at week 16.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bimekizumab (BIMZELX)
What this could lead to
If it works, this could provide a new treatment option for people with painful pustules on hands and feet.
What could go wrong
This is a late-stage trial, but results may not apply to all patients. Side effects are possible, and the drug may not work better than placebo.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Ppp001 20022
RECRUITINGHangzhou, China
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Ppp001 20104
RECRUITINGSeoul, South Korea
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Ppp001 20136
RECRUITINGTianjin, China
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Ppp001 20137
RECRUITINGChengdu, China
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Ppp001 20184
RECRUITINGShenzhen, China
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Ppp001 20193
RECRUITINGHangzhou, China
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Ppp001 20208
RECRUITINGSeongnam-si, South Korea
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Ppp001 20211
RECRUITINGBucheon-si, South Korea
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Ppp001 20214
RECRUITINGBusan, South Korea
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Ppp001 20215
RECRUITINGGwangju, South Korea
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Ppp001 20311
RECRUITINGGuangzhou, China
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Ppp001 20313
RECRUITINGGuangzhou, China
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Ppp001 20344
RECRUITINGJinan, China
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Ppp001 20345
RECRUITINGShanghai, China
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Ppp001 20350
RECRUITINGChongqing, China
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Ppp001 20351
RECRUITINGSeoul, South Korea
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Ppp001 20352
RECRUITINGChengdu, China
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Ppp001 20353
RECRUITINGYinchuan, China
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Ppp001 20354
RECRUITINGSeoul, South Korea
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Ppp001 20355
RECRUITINGJinan, China
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Ppp001 20356
RECRUITINGXi'an, China
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Ppp001 20357
RECRUITINGBeijing, China
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Ppp001 20366
RECRUITINGAnyang-si, South Korea
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Ppp001 20367
RECRUITINGJeonju, South Korea
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Ppp001 40108
RECRUITINGSalford, United Kingdom
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Ppp001 40113
RECRUITINGLondon, United Kingdom
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Ppp001 40203
RECRUITINGBudapest, Hungary
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Ppp001 40230
RECRUITINGValencia, Spain
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Ppp001 40249
RECRUITINGKiel, Germany
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Ppp001 40266
RECRUITINGBadalona, Spain
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Ppp001 40297
RECRUITINGManises, Spain
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Ppp001 40334
RECRUITINGWroclaw, Poland
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Ppp001 40356
RECRUITINGDresden, Germany
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Ppp001 40366
RECRUITINGRostock, Germany
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Ppp001 40396
RECRUITINGRzeszów, Poland
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Ppp001 40515
RECRUITINGBerlin, Germany
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Ppp001 40567
RECRUITINGRoma, Italy
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Ppp001 40604
RECRUITINGWarsaw, Poland
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Ppp001 40625
RECRUITINGWarsaw, Poland
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Ppp001 40626
RECRUITINGBialystok, Poland
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Ppp001 40637
RECRUITINGGdansk, Poland
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Ppp001 40740
RECRUITINGBad Bentheim, Germany
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Ppp001 40743
RECRUITINGSzczecin, Poland
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Ppp001 40747
RECRUITINGMainz, Germany
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Ppp001 40750
RECRUITINGAlicante, Spain
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Ppp001 40757
RECRUITINGPoznan, Poland
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Ppp001 40788
RECRUITINGTorun, Poland
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Ppp001 40816
RECRUITINGBrescia, Italy
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Ppp001 40830
RECRUITINGRozzano, Italy
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Ppp001 40862
RECRUITINGWroclaw, Poland
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Ppp001 40866
RECRUITINGGöttingen, Germany
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Ppp001 40868
RECRUITINGValencia, Spain
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Ppp001 40874
RECRUITINGNice, France
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Ppp001 40875
RECRUITINGAhaus, Germany
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Ppp001 40878
RECRUITINGKatowice, Poland
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Ppp001 40880
RECRUITINGLondon, United Kingdom
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Ppp001 40881
RECRUITINGÚstí nad Labem, Czechia
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Ppp001 40885
RECRUITINGGranada, Spain
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Ppp001 40886
RECRUITINGHellerup, Denmark
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Ppp001 40887
RECRUITINGToulon, France
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Ppp001 40888
RECRUITINGMadrid, Spain
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Ppp001 40889
RECRUITINGMálaga, Spain
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Ppp001 40891
RECRUITINGBielefeld, Germany
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Ppp001 40892
RECRUITINGLübeck, Germany
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Ppp001 40893
RECRUITINGBochum, Germany
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Ppp001 40894
RECRUITINGOrosháza, Hungary
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Ppp001 40895
RECRUITINGDebrecen, Hungary
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Ppp001 40915
RECRUITINGKrakow, Poland
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Ppp001 50233
RECRUITINGBarrie, Canada
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Ppp001 50354
RECRUITINGCalgary, Canada
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Ppp001 50740
RECRUITINGQuébec, Canada
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Ppp001 50745
RECRUITINGColumbus, Ohio, 43213, United States
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Ppp001 50746
RECRUITINGCoral Gables, Florida, 33134, United States
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Ppp001 50749
RECRUITINGFredericton, Canada
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Ppp001 50750
RECRUITINGSurrey, Canada
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Ppp001 50752
RECRUITINGRed Deer, Canada
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Ppp001 50765
RECRUITINGLondon, Canada