New drug BI 764532 enters first human tests for Tough-to-Treat cancers

NCT ID NCT04429087

First seen Nov 01, 2025 · Last updated Apr 24, 2026 · Updated 33 times

Summary

This early-stage study tests a new drug, BI 764532, in adults with advanced small cell lung cancer or other neuroendocrine cancers that have not responded to standard treatments. The drug is designed to help the immune system attack cancer cells. The main goal is to find the highest safe dose and best dosing schedule, with treatment lasting up to 3 years if beneficial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Clínica Universidad de Navarra

    RECRUITING

    Pamplona, 31008, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Clinico Universitario De Valencia

    RECRUITING

    Valencia, 46010, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitari Vall D Hebron

    RECRUITING

    Barcelona, 08035, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital del Mar

    RECRUITING

    Barcelona, 08003, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • National Cancer Center Hospital East

    RECRUITING

    Chiba, Kashiwa, 277-8577, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Technische Universität Dresden

    RECRUITING

    Dresden, 01307, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Maryland School of Medicine

    RECRUITING

    Baltimore, Maryland, 21201, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Pittsburgh Medical Center

    COMPLETED

    Pittsburgh, Pennsylvania, 15232, United States

  • Universitätsklinikum Köln (AöR)

    RECRUITING

    Cologne, 50937, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Universitätsklinikum Würzburg AÖR

    RECRUITING

    Würzburg, 97078, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63108, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Winship Cancer Institute

    RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.