New hope for advanced cancer: First-in-Human trial launches

NCT ID NCT07395258

First seen Feb 13, 2026 · Last updated Apr 28, 2026 · Updated 14 times

Summary

This study tests a new drug, BI 3923948, in people with advanced solid tumors that have spread and are hard to treat. About 60 adults will receive the drug alone or with an immunotherapy (checkpoint inhibitor) to find the safest dose and see if it shrinks tumors. The drug is injected directly into tumors, and participants are closely monitored for side effects and response.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CTR Leon Berard

    NOT_YET_RECRUITING

    Lyon, 69373, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fred Hutchinson Cancer Research Center

    NOT_YET_RECRUITING

    Seattle, Washington, 98109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Clinico De Valencia (INCLIVA)

    NOT_YET_RECRUITING

    Valencia, 46010, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Clínic de Barcelona

    NOT_YET_RECRUITING

    Barcelona, 08036, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Indiana University

    NOT_YET_RECRUITING

    Indianapolis, Indiana, 46202, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Gustave Roussy

    NOT_YET_RECRUITING

    Villejuif, 94800, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Karolinska Universitetssjukhuset Stockholm

    NOT_YET_RECRUITING

    Stockholm, 17177, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The University of Texas MD Anderson Cancer Center

    NOT_YET_RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Minnesota

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Universitätsklinikum Heidelberg

    NOT_YET_RECRUITING

    Heidelberg, 69120, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.