New pill targets rare immune diseases in early trial

NCT ID NCT06878365

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 24 times

Summary

This early-stage study tests a new medicine called BI 3000202 in 16 adults with rare immune disorders like Aicardi-Goutières syndrome. Participants take the drug as tablets for 40 weeks to see if it is safe and how the body processes it. The goal is to control the disease, not cure it.

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Contacts and locations

Locations

  • ASST degli Spedali Civili di Brescia

    Brescia, 25123, Italy

  • Azienda Sanitaria Universitaria Giuliano Isontina

    Trieste, 34124, Italy

  • Barzilai Medical Center

    Ashkelon, 7830604, Israel

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • HOP Tenon

    Paris, 75020, France

  • Hospital Universitari Vall d'Hebron

    Barcelona, 08035, Spain

  • Hospital Universitario La Paz

    Madrid, 28046, Spain

  • Hospital Virgen del Rocío

    Seville, 41013, Spain

  • Hôpital Gui de Chauliac

    Montpellier, 34295, France

  • Hôpital Necker

    Paris, 75015, France

  • Medizinische Hochschule Hannover

    Hanover, 30625, Germany

  • Royal Free Hospital

    London, NW3 2QG, United Kingdom

  • Royal Infirmary of Edinburgh

    Edinburgh, EH16 4SA, United Kingdom

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

  • ULS de Santa Maria, E.P.E

    Lisbon, 1649-035, Portugal

  • ULS de Santo Antônio, E.P.E - Centro Hospitalar Universitário de Santo António

    Porto, 4099-001, Portugal

  • Universitair Ziekenhuis Gent

    Ghent, 9000, Belgium

  • University of California San Francisco

    San Francisco, California, 94143, United States

  • Universitätsklinikum Carl Gustav Carus Dresden

    Dresden, 01307, Germany

  • Universitätsklinikum Tübingen

    Tübingen, 72076, Germany

Conditions

Explore the condition pages connected to this study.