First human test of new cancer drug halted early

NCT ID NCT04249843

Summary

This early-stage study aimed to test the safety and find the right dose of an experimental drug called BGB-3245 in people with advanced solid tumors that had stopped responding to other treatments. It specifically enrolled patients whose tumors had certain genetic changes in the BRAF gene. The study was terminated, and its main goal was to understand how the body processes the drug and what side effects it might cause.

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Contacts and locations

Locations

  • Blacktown Hospital

    Blacktown, New South Wales, 2148, Australia

  • Cedars Sinai Medical Center

    Beverly Hills, California, 90212, United States

  • MD Anderson

    Houston, Texas, 77030, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • One Clinical Research

    Nedlands, Perth, 6009, Australia

  • Peter MacCallum Cancer Centre

    Melbourne, Victoria, 2010, Australia

  • The Kinghorn Cancer Centre, St Vincent Hospital Sydney

    Sydney, New South Wales, 2010, Australia

  • University of Virginia Comprehensive Cancer Centre

    Charlottesville, Virginia, 22903, United States

Conditions

Explore the condition pages connected to this study.