New pill could tame stubborn hives

NCT ID NCT07005713

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tested an experimental oral drug called BGB-16673 in 34 adults with chronic spontaneous urticaria (CSU), a condition causing persistent hives and itching. The study was double-blind and placebo-controlled, meaning neither patients nor doctors knew who got the real drug. The main goals were to check safety and how the drug moves through the body, not yet to prove it works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

BGB-16673 (an oral drug)

What this could lead to

If successful, this could lead to a new oral treatment option for people with chronic hives that are not controlled by antihistamines.

What could go wrong

This is a very early Phase 1b trial with only 34 participants, focused on safety and dosing. It is too small and early to know if the drug will effectively reduce hives or be safe long-term.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic idiopathic urticaria Chronic Urticaria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chengdu Second Peoples Hospital

    Chengdu, Sichuan, 610021, China

  • Dermatology Hospital of Southern Medical University

    Guangzhou, Guangdong, China

  • Hangzhou First Peoples Hospital

    Hangzhou, Zhejiang, 310006, China

  • Peking University Third Hospital

    Beijing, Beijing Municipality, 100000, China

  • The First Affiliated Hospital of Chongqing Medical University

    Chongqing, Chongqing Municipality, 630014, China

  • The First Affiliated Hospital of Wenzhou Medical University

    Wenzhou, Zhejiang, 325000, China

  • Union Hospital of Tongji Medical College, Huazhong University of Science and Technology

    Wuhan, Hubei, 430022, China

  • Xiangya Hospital of Central South University

    Changsha, Hunan, 410008, China