New smart drug targets Hard-to-Treat cancers in early human trial

NCT ID NCT06625593

Recruiting now Disease control Sponsor: BeOne Medicines Source: ClinicalTrials.gov ↗

First seen Sep 30, 2025 · Last updated Apr 30, 2026 · Updated 22 times

Summary

This early-phase study tests a new drug called BG-C137 in people with advanced solid tumors that have not responded to standard treatments. The drug is designed to deliver a cancer-killing agent directly to cells with a specific marker (FGFR2b). The main goals are to check safety, find the right dose, and see if it shrinks tumors. About 168 participants will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Affiliated Hospital of Jiangnan University South Campus
RECRUITING

Wuxi, Jiangsu, 214122, China
Affiliated Zhongshan Hospital of Fudan University
RECRUITING

Shanghai, Shanghai Municipality, 200032, China
Anhui Provincial Hospital
RECRUITING

Hefei, Anhui, 230000, China
Asan Medical Center
RECRUITING

SongpaGu, Seoul Teugbyeolsi, 05505, South Korea
Beijing Cancer Hospital
RECRUITING

Beijing, Beijing Municipality, 100142, China
Beijing Friendship Hospital, Capital Medical University
RECRUITING

Beijing, Beijing Municipality, 100050, China
Blacktown Cancer and Haematology Centre
RECRUITING

Blacktown, New South Wales, NSW 2148, Australia
Cabrini Hospital Malvern
RECRUITING

Malvern East, Victoria, VIC 3144, Australia
Cha Bundang Medical Center, Cha University
RECRUITING

BundangGu SeongnamSi, Gyeonggi-do, 13496, South Korea
Fred Hutchinson Cancer Research Center
RECRUITING

Seattle, Washington, 98109-4433, United States
Fudan University Shanghai Cancer Centerpudong
RECRUITING

Shanghai, Shanghai Municipality, 201321, China
Fujian Medical University Union Hospital
RECRUITING

Fuzhou, Fujian, 350001, China
Gachon University Gil Medical Center
RECRUITING

NamdongGu, Incheon Gwang'yeogsi, 21565, South Korea
Gangnam Severance Hospital, Yonsei University Health System
RECRUITING

Seoul, Seoul Teugbyeolsi, 06273, South Korea
Harbin Medical University Cancer Hospital
RECRUITING

Harbin, Heilongjiang, 150000, China
Henan Cancer Hospital
RECRUITING

Zhengzhou, Henan, 450000, China
Heping Hospital Affiliated to Changzhi Medical College
RECRUITING

Changzhi, Shanxi, 046000, China
Hubei Cancer Hospital
RECRUITING

Wuhan, Hubei, 430079, China
Icon Cancer Centre South Brisbane
RECRUITING

South Brisbane, Queensland, QLD 4101, Australia
Jiangsu Province Hospital
RECRUITING

Nanjing, Jiangsu, 210029, China
Kyungpook National University Chilgok Hospital
RECRUITING

BukGu, Gyeongsangbukdo, 41404, South Korea
Liaoning Cancer Hospital and Institute
RECRUITING

Shenyang, Liaoning, 110042, China
Liverpool Hospital
RECRUITING

Liverpool, New South Wales, NSW 2170, Australia
Mayo Clinic Rochester
COMPLETED

Rochester, Minnesota, 55905-0001, United States
Md Anderson Cancer Center
RECRUITING

Houston, Texas, 77030-3907, United States
Monash Health
RECRUITING

Clayton, Victoria, VIC 3168, Australia
Nanjing Drum Tower Hospital,the Affiliated Hospital of Nanjing University Medical School
RECRUITING

Nanjing, Jiangsu, 210008, China
Samsung Medical Center
RECRUITING

GangnamGu, Seoul Teugbyeolsi, 06351, South Korea
Seoul National University Bundang Hospital
RECRUITING

Seongnam-si, Gyeonggi-do, 13620, South Korea
Seoul National University Hospital
RECRUITING

Seoul, Seoul Teugbyeolsi, 03080, South Korea
Severance Hospital Yonsei University Health System
RECRUITING

SeodaemunGu, Seoul Teugbyeolsi, 03722, South Korea
Shandong Cancer Hospital
RECRUITING

Jinan, Shandong, 250117, China
Shanghai East Hospital Branch Hospital
RECRUITING

Shanghai, Shanghai Municipality, 200123, China
Shanxi Provincial Cancer Hospital
RECRUITING

Taiyuan, Shanxi, 030013, China
Sichuan Academy of Medical Sciences and Sichuan Provincial Peoples Hospital
RECRUITING

Chengdu, Sichuan, 610071, China
The Affiliated Hospital of Qingdao University Branch North
RECRUITING

Qingdao, Shandong, 266000, China
The Affiliated Hospital of Xuzhou Medical University Kunpeng Road Branch
RECRUITING

Xuzhou, Jiangsu, 221000, China
The First Affiliated Hospital of Bengbu Medical University
RECRUITING

Bengbu, Anhui, 233004, China
The First Affiliated Hospital of Henan University of Science and Technology
RECRUITING

Luoyang, Henan, 471003, China
The First Affiliated Hospital of Xian Jiaotong University
RECRUITING

Xi'an, Shaanxi, 710061, China
The First Affiliated Hospital of Xinxiang Medical University
RECRUITING

Xinxiang, Henan, 453100, China
The Fourth Hospital of Hebei Medical University
RECRUITING

Shijiazhuang, Hebei, 050011, China
The Second Affiliated Hospital of Shandong First Medical University
RECRUITING

Taian, Shandong, 271099, China
The Second Hospital of Anhui Medical University
RECRUITING

Hefei, Anhui, 230601, China
The Tumor Hospital Affiliated to Guangxi Medical Universitywuxiang Branch
RECRUITING

Nanning, Guangxi, 530201, China
Tianjin Medical University Cancer Institute and Hospital
RECRUITING

Tianjin, Tianjin Municipality, 300060, China
University of Wisconsin
RECRUITING

Madison, Wisconsin, 53792-0001, United States
Usc Norris Comprehensive Cancer Center (Nccc)
RECRUITING

Los Angeles, California, 90089-1019, United States
Weifang Peoples Hospital Beichen Branch
RECRUITING

Weifang, Shandong, 261057, China
Yale Cancer Center
RECRUITING

New Haven, Connecticut, 06520-8028, United States
Zhejiang Cancer Hospital
RECRUITING

Hangzhou, Zhejiang, 310022, China
Zhongshan Hospital Xiamen University
RECRUITING

Xiamen, Fujian, 361004, China

Conditions

Explore the condition pages connected to this study.

ADVANCED SOLID TUMOR