New cancer drug shows promise in early trial for Hard-to-Treat tumors

NCT ID NCT06568614

First seen Feb 05, 2026 · Last updated May 15, 2026 · Updated 14 times

Summary

This study tested a new drug called BG-89894 in 29 people with advanced solid tumors that have a specific genetic change (MTAP deletion). The main goals were to check safety, find the best dose, and see if the drug can shrink tumors. The study was stopped early, but the information gathered will help design future trials.

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Contacts and locations

Locations

  • Beijing Cancer Hospital

    Beijing, Beijing Municipality, 100142, China

  • Beijing Tsinghua Changgung Hospital

    Beijing, Beijing Municipality, 102218, China

  • Blacktown Cancer and Haematology Centre

    Blacktown, New South Wales, NSW 2148, Australia

  • Cancer Hospital Chinese Academy of Medical Sciences

    Beijing, Beijing Municipality, 100021, China

  • Cancer Research South Australia

    Adelaide, South Australia, SA 5000, Australia

  • Columbia University Irving Medical Center

    New York, New York, 10032-3725, United States

  • Guangdong Provincial Peoples Hospital Huifu Branch

    Guangzhou, Guangdong, 510120, China

  • Guangxi Medical University Cancer Hospital

    Nanning, Guangxi, 530021, China

  • Jiangsu Province Hospital

    Nanjing, Jiangsu, 210029, China

  • Linear Clinical Research

    Nedlands, Western Australia, WA 6009, Australia

  • Next Virginia

    Fairfax, Virginia, 22031, United States

  • Shanghai Pulmonary Hospital

    Shanghai, Shanghai Municipality, 200433, China

  • Sidney Kimmel Comprehensive Cancer At Johns Hopkins

    Baltimore, Maryland, 21287, United States

  • St Vincents Hospital

    Fitzroy, Victoria, VIC 3065, Australia

  • The First Hospital of China Medical University Hunnan Branch

    Shenyang, Liaoning, 110167, China

  • The Fourth Hospital of Hebei Medical University

    Shijiazhuang, Hebei, 050011, China

  • Tianjin Medical University Cancer Institute and Hospital

    Tianjin, Tianjin Municipality, 300060, China

  • Union Hospital of Tongji Medical College, Huazhong University of Science and Technology

    Wuhan, Hubei, 430022, China

  • Washington University School of Medicine

    St Louis, Missouri, 63110-1010, United States

  • West China Hospital, Sichuan University

    Chengdu, Sichuan, 610041, China

Conditions

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