Experimental cocktail targets Hard-to-Treat cancers
NCT ID NCT04840589
First seen Nov 01, 2025 · Last updated Jun 12, 2026 · Updated 38 times
Summary
This early-phase trial tested a combination of a BET inhibitor (ZEN003694) with immunotherapy drugs (nivolumab with or without ipilimumab) in people with advanced solid tumors that no longer respond to standard treatments. The goal was to find the safest dose and see if the combo could shrink or stabilize tumors. The study involved 66 participants but has been suspended.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Case Western Reserve University
Cleveland, Ohio, 44106, United States
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Montefiore Medical Center - Moses Campus
The Bronx, New York, 10467, United States
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Montefiore Medical Center-Einstein Campus
The Bronx, New York, 10461, United States
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Montefiore Medical Center-Weiler Hospital
The Bronx, New York, 10461, United States
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Mount Sinai Hospital
New York, New York, 10029, United States
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National Cancer Institute Developmental Therapeutics Clinic
Bethesda, Maryland, 20892, United States
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
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Oregon Health and Science University
Portland, Oregon, 97239, United States
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University of Pittsburgh Cancer Institute (UPCI)
Pittsburgh, Pennsylvania, 15232, United States
Conditions
Explore the condition pages connected to this study.