New cocktail of immunotherapy, targeted drug, chemo, and radiation takes on lung cancer
NCT ID NCT07538258
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial is testing a powerful combination of treatments for people with limited-stage small cell lung cancer (LS-SCLC) who have not had prior therapy. Participants will receive an immunotherapy drug (benmelstobart), an anti-angiogenic pill (anlotinib), standard chemotherapy (cisplatin or carboplatin plus etoposide), and radiation to the chest. The goal is to see how many tumors shrink or disappear. The study will enroll 27 people and follow them for up to 2 years on maintenance therapy. Because it is a small, single-arm study without a comparison group, results will be preliminary.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
benmelstobart (immunotherapy), anlotinib (anti-angiogenic drug), cisplatin or carboplatin (chemotherapy), etoposide (chemotherapy), and thoracic radiation
What this could lead to
If successful, this combination could improve tumor shrinkage and delay progression in limited-stage small cell lung cancer, potentially offering a more effective first-line treatment option.
What could go wrong
This is a small, early-phase (2) single-arm study with only 27 participants, so results may not be generalizable. Combining multiple therapies increases the risk of serious side effects, and the trial has not yet started recruiting.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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