Oral drug shows promise in shrinking tumors for rare genetic cancer syndrome

NCT ID NCT03401788

First seen Apr 14, 2026 ยท Last updated Apr 14, 2026

Summary

This study is testing an oral drug called belzutifan for people with von Hippel-Lindau (VHL) disease who have kidney tumors. The goal is to see if continuous daily treatment can shrink these tumors and delay the need for surgery. The study will also monitor how the drug affects other tumors caused by VHL and track any side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Contacts and locations

Locations

  • Aarhus University Hospital

    Aarhus, Denmark

  • Cambridge University Hospital

    Cambridge, United Kingdom

  • Hospital Georges Pompidou

    Paris, France

  • Huntsman Cancer Institute

    Salt Lake City, Utah, 84112, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • University of Pennsylvania Medical Center

    Philadelphia, Pennsylvania, 19104, United States

  • University of Pittsburgh Medical Center

    Pittsburgh, Pennsylvania, 15232, United States

  • Vanderbilt Medical Center

    Nashville, Tennessee, 37232, United States

Conditions

Explore the condition pages connected to this study.