Gene type may affect how cancer drug works in patients

NCT ID NCT02680795

First seen Nov 01, 2025 · Last updated May 10, 2026 · Updated 24 times

Summary

This early-phase study looked at how the cancer drug belinostat is processed in the body based on a person's UGT1A1 gene type. Seventeen adults with advanced solid tumors or blood cancers that had come back or stopped responding to treatment took part. The goal was to measure drug levels and safety, not to treat the cancer directly.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEMATOLOGICAL MALIGNANCIES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Gabrail Cancer Center Research

    Canton, Ohio, 44718, United States

  • John Wayne Cancer Institute @ Providence Saint John's Health Center

    Santa Monica, California, 90404, United States

  • The Oncology Institute of Hope and Innovation

    Whittier, California, 90603, United States

Conditions

Explore the condition pages connected to this study.