Gene-Guided drug dosing could improve treatment for rare cancer
NCT ID NCT06406465
First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 32 times
Summary
This study aims to find the best dose of the drug belinostat for people with high-grade neuroendocrine carcinomas based on their genetic makeup. Some people have a gene variant that affects how quickly their body processes belinostat, so adjusting the dose may reduce side effects and improve outcomes. About 60 adults with this rare cancer will receive belinostat along with two other chemotherapy drugs, and those who benefit may continue belinostat alone for up to 5 years.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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