Which bathing method best fights superbugs in the ICU?

NCT ID NCT07364435

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
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First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two different bed bathing methods to see which better reduces vancomycin-resistant Enterococcus (VRE) bacteria on the skin of intensive care unit patients. 210 adults were randomly assigned to daily baths with either a 4% chlorhexidine gluconate solution or disposable antibacterial wipes. Skin swabs were taken over three weeks to track VRE levels, aiming to find the most effective hygiene practice for preventing the spread of this hard-to-treat germ.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Chlorhexidine gluconate 4% solution and disposable antibacterial wipes
What this could lead to
If effective, these bathing methods could help reduce the spread of antibiotic-resistant bacteria in hospital intensive care units.
What could go wrong
This is a completed study, but the results may not apply to all ICU settings or patient populations. The methods only target skin colonization, not infections elsewhere.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

210 people

The number who actually took part.

Started

Sep 2024

Finished

Aug 2025

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients aged 18 years and older * Patients admitted to the intensive care unit * Expected ICU stay of at least 48 hours * Patients requiring daily bed bathing Exclusion Criteria: * Known hypersensitivity to chlorhexidine * Extensive skin lesions or burns * Patients colonized or infected with VRE at ICU admission * Pregnancy

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Contacts and locations

Locations

  • Basaksehir Pine and Sakura City Hospital

    Istanbul, Istanbul, 34000, Turkey (Türkiye)