Which bathing method best fights superbugs in the ICU?
NCT ID NCT07364435
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested two different bed bathing methods to see which better reduces vancomycin-resistant Enterococcus (VRE) bacteria on the skin of intensive care unit patients. 210 adults were randomly assigned to daily baths with either a 4% chlorhexidine gluconate solution or disposable antibacterial wipes. Skin swabs were taken over three weeks to track VRE levels, aiming to find the most effective hygiene practice for preventing the spread of this hard-to-treat germ.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Chlorhexidine gluconate 4% solution and disposable antibacterial wipes
- What this could lead to
- If effective, these bathing methods could help reduce the spread of antibiotic-resistant bacteria in hospital intensive care units.
- What could go wrong
- This is a completed study, but the results may not apply to all ICU settings or patient populations. The methods only target skin colonization, not infections elsewhere.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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210 people
The number who actually took part.
- Started
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Sep 2024
- Finished
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Aug 2025
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients aged 18 years and older * Patients admitted to the intensive care unit * Expected ICU stay of at least 48 hours * Patients requiring daily bed bathing Exclusion Criteria: * Known hypersensitivity to chlorhexidine * Extensive skin lesions or burns * Patients colonized or infected with VRE at ICU admission * Pregnancy
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Basaksehir Pine and Sakura City Hospital
Istanbul, Istanbul, 34000, Turkey (Türkiye)