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Beads vs. vacuum: major trial seeks best way to save shattered legs

NCT ID NCT05615844

Recruiting now Disease control Sponsor: University of Maryland, Baltimore Source: ClinicalTrials.gov ↗

Summary

This study aims to find the better temporary wound care method for severe open leg fractures that need multiple clean-out surgeries. It will compare two common approaches: placing antibiotic beads in the wound versus using a vacuum-sealed dressing (wound VAC). The goal is to see which method leads to fewer serious complications like death, amputation, infection, or the need for more surgeries within six months.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Bon Secours Mercy Health

    RECRUITING

    Cincinnati, Ohio, 45237, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Bryan Medical Center

    RECRUITING

    Lincoln, Nebraska, 68506, United States

    Contact

  • Cedars-Sinai Medical Center

    RECRUITING

    Los Angeles, California, 90048, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Dartmouth-Hitchcock Medical Center

    RECRUITING

    Lebanon, New Hampshire, 03766, United States

    Contact

  • Dignity Health Chandler Regional Medical Center

    RECRUITING

    Chandler, Arizona, 85224, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hamilton Health Sciences

    RECRUITING

    Hamilton, Ontario, L8L 2X2, Canada

    Contact

  • Indiana University

    RECRUITING

    Indianapolis, Indiana, 46202, United States

    Contact

  • Inova Fairfax

    RECRUITING

    Falls Church, Virginia, 22042, United States

    Contact

  • London Health Sciences Centre

    RECRUITING

    London, Ontario, N6C 2R6, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ortegon Health & Science University

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact

  • Prisma Health

    RECRUITING

    Greenville, South Carolina, 29605, United States

    Contact

  • Prisma Health - Midlands

    RECRUITING

    Columbia, South Carolina, 29203, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Royal Columbian Hospital

    RECRUITING

    New Westminster, British Columbia, V3L 3W7, Canada

    Contact

  • Sanford Health

    RECRUITING

    Sioux Falls, South Dakota, 57104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sanford Medical Center

    RECRUITING

    Fargo, North Dakota, 58103, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Slocum Center

    RECRUITING

    Eugene, Oregon, 97401, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Luke's University Health Network

    RECRUITING

    Bethlehem, Pennsylvania, 18015, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Ottawa Hospital

    RECRUITING

    Ottawa, Ontario, K1Y 4E9, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Medical Center of Southern Nevada

    WITHDRAWN

    Las Vegas, Nevada, 89102, United States

  • University of British Columbia

    RECRUITING

    Vancouver, British Columbia, V5Z 1M9, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of California, Davis

    RECRUITING

    Davis, California, 95616, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of California, Irvine

    RECRUITING

    Orange, California, 92868, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Cincinnati

    RECRUITING

    Cincinnati, Ohio, 45219, United States

    Contact

  • University of Florida

    RECRUITING

    Gainesville, Florida, 32611, United States

    Contact

  • University of Maryland Capital Region Health

    RECRUITING

    Largo, Maryland, 20774, United States

    Contact

  • University of Maryland, R Adams Cowley Shock Trauma Center

    RECRUITING

    Baltimore, Maryland, 21201, United States

    Contact Phone: •••-•••-••••

    Contact

  • University of Miami

    RECRUITING

    Miami, Florida, 33146, United States

    Contact

  • University of Mississippi

    RECRUITING

    University, Mississippi, 38677, United States

    Contact

  • University of Southern California

    RECRUITING

    Los Angeles, California, 90033, United States

    Contact

  • University of Utah

    RECRUITING

    Salt Lake City, Utah, 84112, United States

    Contact

  • University of Wisconsin

    WITHDRAWN

    Madison, Wisconsin, 53792, United States

  • Yale University

    RECRUITING

    New Haven, Connecticut, 06520, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

OPEN TÍBIA FRACTURE