New CAR-T therapy targets Hard-to-Treat blood cancer

NCT ID NCT07195617

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 26 times

Summary

This early study tests a new type of CAR-T cell therapy (BCMA-GPRC5D) in 10 adults with relapsed/refractory multiple myeloma who have already tried at least three prior treatments. The therapy uses the patient's own immune cells, modified to attack two cancer targets, and is given as a single infusion. The main goals are to check safety and see if the treatment can control the cancer. Because multiple myeloma often requires ongoing management, this is not expected to be a cure.

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