Can a TB vaccine stop bladder cancer from coming back?
NCT ID NCT06747455
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 3 trial tests whether a therapeutic BCG vaccine, given directly into the bladder, can prevent non-muscle-invasive bladder cancer from returning after surgery. About 439 adults with intermediate- or high-risk cancer are participating. The study compares BCG to an active control, with follow-up for up to 2 years to see who remains cancer-free.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
BCG (Bacillus Calmette-Guérin) vaccine
What this could lead to
If successful, this could provide a proven way to prevent bladder cancer from coming back after surgery, reducing the need for more aggressive treatments.
What could go wrong
This is a Phase 3 trial, but results are not yet available. BCG therapy can cause side effects like bladder irritation or infection, and it may not work for everyone.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Fudan University Shanghai Cancer Center
Shanghai, China