New drug shows promise for bulging eyes in thyroid disease

NCT ID NCT05524571

First seen Nov 01, 2025 · Last updated May 04, 2026 · Updated 22 times

Summary

This study tested a drug called batoclimab for people with active thyroid eye disease, a condition that causes eye bulging, redness, and swelling. 86 adults with moderate to severe symptoms received weekly injections of either batoclimab or a placebo for 24 weeks. The main goal was to see if the drug could reduce eye protrusion by at least 2 millimeters without worsening the other eye.

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Contacts and locations

Locations

  • Site Number - 1512

    Winston-Salem, North Carolina, 27157, United States

  • Site Number - 1513

    Rochester, Minnesota, 55905, United States

  • Site Number - 1518

    Milwaukee, Wisconsin, 53226, United States

  • Site Number - 1521

    Seattle, Washington, 98104, United States

  • Site Number - 1524

    McAllen, Texas, 78503, United States

  • Site Number - 1525

    Portland, Oregon, 97239, United States

  • Site Number - 1526

    Livonia, Michigan, 48152, United States

  • Site Number - 3605

    Barcelona, 08035, Spain

  • Site Number - 4672

    Brussels, 1070, Belgium

  • Site Number - 4673

    Brussels, 1200, Belgium

  • Site Number - 4674

    Liège, 4000, Belgium

  • Site Number - 4950

    Ankara, 6100, Turkey (Türkiye)

  • Site Number - 4951

    Istanbul, 34010, Turkey (Türkiye)

  • Site Number - 4952

    Adana, 13860, Turkey (Türkiye)

  • Site Number - 6603

    Mainz, Rhineland-Palatinate, 55131, Germany

  • Site Number - 7550

    Budapest, 1133, Hungary

  • Site Number - 7551

    Pécs, 7621, Hungary

  • Site Number - 7552

    Pécs, 7623, Hungary

  • Site Number - 7565

    Sydney, 2000, Australia

  • Site Number - 7570

    Christchurch, 8013, New Zealand

  • Site Number - 7572

    Hamilton, 3204, New Zealand

  • Site Number - 9200

    Bratislava, 82606, Slovakia

  • Site Number - 9201

    Bratislava, 85107, Slovakia

  • Site Number - 9202

    Trenčín, 91101, Slovakia

  • Site Number - 9203

    Bratislava, 81108, Slovakia

  • Site Number - 9302

    Ventspils, LV-3601, Latvia

  • Site Number -1510

    Sarasota, Florida, 34239, United States

  • Site Number -1511

    Morgantown, West Virginia, 26506, United States

  • Site Number -1514

    Torrance, California, 90502, United States

  • Site Number -1515

    Bellaire, Texas, 77401, United States

  • Site Number -1516

    Louisville, Kentucky, 40202, United States

  • Site Number -1517

    San Francisco, California, 94143, United States

  • Site Number -1519

    San Antonio, Texas, 78215, United States

  • Site Number -1520

    Pasadena, California, 91107, United States

  • Site Number -1990

    San Juan, 00921, Puerto Rico

  • Site Number -3600

    Santiago de Compostela, 15706, Spain

  • Site Number -3601

    Madrid, 28007, Spain

  • Site Number -3602

    Barcelona, 08006, Spain

  • Site Number -3603

    Valencia, 46026, Spain

  • Site Number -3604

    Madrid, 28034, Spain

  • Site Number -3606

    Seville, 41009, Spain

  • Site Number -4670

    Ghent, B-9000, Belgium

  • Site Number -4671

    Bruges, 8000, Belgium

  • Site Number -9300

    Riga, LV-1006, Latvia

  • Site Number -9301

    Ogre, LV-5001, Latvia

Conditions

Explore the condition pages connected to this study.