Scientists probe Skin's hidden defenses before yellow fever shot
NCT ID NCT07636551
First seen Jun 25, 2026 · Last updated Aug 14, 2026 · Updated 3 times
Summary
This study looks at immune cells in the skin of 40 healthy adults who have never received a yellow fever vaccine. Researchers will take small skin samples and blood to measure baseline levels of memory T cells. The goal is to understand the skin's natural immune state before vaccination, which may help improve future vaccines against mosquito-borne diseases.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could help design better vaccines for mosquito-borne diseases like yellow fever by understanding how the skin's immune system works before vaccination.
- What could go wrong
- This is a small, early observational study with only 40 participants, so results may not apply to everyone. It does not test any treatment or vaccine.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Clinical Trial Site of the Institute of Tropical Medicine
RECRUITINGAntwerp, Belgium
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Other studies related to the condition(s) this trial covers.