Scientists test 'Off-the-Shelf' cell therapy to wipe out leukemia before transplant

NCT ID NCT05942599

Summary

This early-stage trial is testing a new, 'ready-made' cell therapy called BE CAR-33 in children whose acute myeloid leukemia (AML) has returned. The therapy uses healthy donor immune cells that are genetically edited to find and kill leukemia cells. The main goal is to see if this treatment is safe and can clear the cancer to prepare children for a planned bone marrow transplant, which aims to keep the cancer from coming back.

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Contacts and locations

Locations

  • Great Ormond Street Hospital for Children

    London, WC1N3JH, United Kingdom

Conditions

Explore the condition pages connected to this study.