Hope for a devastating childhood disease: drug trial aims to halt progression

NCT ID NCT03921554

Summary

This study tested a drug called baricitinib for children with Aicardi Goutières Syndrome (AGS), a rare and severe genetic disorder that causes brain damage and affects many organs. The goal was to see if the drug, taken for a year, could safely reduce harmful inflammation and help stabilize or improve children's neurological function and development. It involved 54 participants, including infants as young as one month old.

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Contacts and locations

Locations

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.