New CAR t therapy targets tough lymphoma in early trial

NCT ID NCT05370430

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 23 times

Summary

This early-phase study tests a new treatment for people with B-cell non-Hodgkin's lymphoma that has come back or not responded to standard therapy. The treatment uses the patient's own immune cells, modified to target a protein called BAFFR on cancer cells. The main goals are to check safety and find the best dose in 36 adults.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Atrium Health Levine Cancer Institute - Morehead

    RECRUITING

    Charlotte, North Carolina, 28204, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • City of Hope Medical Center

    RECRUITING

    Duarte, California, 91010, United States

    Contact

    Contact Email: •••••@•••••

  • Providence Swedish Cancer Institute

    RECRUITING

    Seattle, Washington, 98104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Stanford University

    RECRUITING

    Stanford, California, 94305, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Kansas Hospital

    RECRUITING

    Kansas City, Kansas, 66160, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Minnesota

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.