New CAR t therapy targets BAFFR to fight Hard-to-Treat leukemia

NCT ID NCT04690595

First seen Feb 28, 2026 · Last updated May 15, 2026 · Updated 6 times

Summary

This early-phase study tests a new type of CAR T cell therapy that targets a protein called BAFFR on leukemia cells. It is for adults with B-cell acute lymphoblastic leukemia that has come back or not responded to at least two prior treatments. The main goal is to check safety and side effects, while also seeing if the therapy can shrink or eliminate the cancer.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

Conditions

Explore the condition pages connected to this study.