New CAR-T therapy targets stubborn leukemia and lymphoma

NCT ID NCT06916767

First seen Nov 11, 2025 · Last updated May 06, 2026 · Updated 17 times

Summary

This early-phase study tests a new type of immune cell therapy called LMY-920 for people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) that has not responded to standard treatments. The therapy uses a patient's own immune cells, modified to attack cancer cells through a protein called BAFF. The study aims to find the safest dose and see if it can shrink tumors or control the disease. It involves 18 adults who have already tried at least two other treatments.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Case Comprehensive Cancer Center, Cleveland Clinic Foundation Taussig Cancer Institute

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact

Conditions

Explore the condition pages connected to this study.