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Zinc toothpaste takes on bad breath in new study

NCT ID NCT07398378

Symptom relief Sponsor: Colgate Palmolive Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a toothpaste with zinc citrate reduces bad breath better than a regular fluoride toothpaste. About 80 adults with moderate to strong bad breath will brush with one of the two toothpastes for three weeks. Researchers will measure breath odor using a panel of trained judges.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

80 people

The number who actually took part.

Started

Jun 2026

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18-70 years, inclusive. * Availability for the full three-week duration of the study. * Good general health. * Initial mean oral malodor (organoleptic) score ≥ 6.0 and ≤ 8.4. * Signed informed consent form. Exclusion Criteria: * Presence of orthodontic bands. * Tumors of the soft or hard tissues of the oral cavity. * Advanced periodontal disease (e.g., purulent exudate, tooth mobility, and/or extensive loss of periodontal attachment or alveolar bone). * Five (5) or more carious lesions requiring immediate restorative treatment. * Use of antibiotics within one (1) month prior to study entry. * Participation in any other clinical study or test panel within one (1) month prior to study entry. * Dental prophylaxis within two (2) weeks prior to the initial examination. * History of allergies to oral care/personal care products or their ingredients. * Use of prescription medications that might interfere with study outcomes. * Medical condition that prevents fasting (no food or drink) for up to four (4) hours. * History of drug and/or alcohol abuse. * Pregnant or lactating (self-reported).

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Oral malodor

Contacts and locations

Locations

  • West China Dental Institute of Chengdu

    Chengdu, Sichuan, 610041, China

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