Engineered immune cells take aim at deadliest lung cancer
NCT ID NCT07509034
First seen Apr 11, 2026 · Last updated Apr 28, 2026 · Updated 2 times
Summary
This early-phase study tests a new treatment for people with extensive-stage small cell lung cancer or similar neuroendocrine cancers that did not respond to or came back after standard therapy. The treatment uses the patient's own immune cells (T cells) that are modified in a lab to recognize and attack a protein called B7-H3 found on cancer cells. Up to 40 adults will receive the modified cells after a short course of chemotherapy, and researchers will monitor safety and tumor response for up to 15 years.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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