Engineered immune cells take aim at deadliest lung cancer

NCT ID NCT07509034

First seen Apr 11, 2026 · Last updated Jun 15, 2026 · Updated 12 times

Summary

This early-phase study tests a personalized cell therapy for people with extensive-stage small cell lung cancer or similar neuroendocrine cancers that came back after standard treatment. Researchers take a patient's own immune cells, modify them to recognize a protein called B7-H3 found on cancer cells, and infuse them back to attack the tumor. The main goals are to find the safest dose and see if the treatment can control the disease.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

neuroendocrine carcinoma Recurrence small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.