New drug combo offers hope for rare blood cancer patients without chemo
NCT ID NCT03620903
First seen Jan 07, 2026 · Last updated May 14, 2026 · Updated 27 times
Summary
This study tests a chemotherapy-free combination of three drugs (bortezomib, rituximab, ibrutinib) in 53 people with newly diagnosed Waldenström's macroglobulinemia, a rare blood cancer. The goal is to see if this approach can control the disease for at least one year with fewer side effects than standard chemo. Participants receive the drugs in cycles, and researchers track how long the cancer stays under control and how well patients respond.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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'Alexandra' General Hospital of Athens
Athens, 11528, Greece
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DIAKO Ev. Diakonie-Krankenhaus gGmbH, Med. Klinik II
Bremen, 28239, Germany
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Gemeinschaftspraxis Dres. Rudolf Schlag, Björn Schöttker, Joachim Haas
Würzburg, 97080, Germany
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Hämato-Onkologische Gemeinschaftspraxis Pasing-Fürstenfeldbruck
München, 81241, Germany
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Kliniken Maria Hilf GmbH (Krankenhaus St. Franziskus), Medizinische Klinik I (Klinik f. Hämatologie, Onkologie, Gastroentereologie)
Mönchengladbach, 41063, Germany
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Kliniken Ostalb Stauferklinikum Schwäbisch Gmünd, Zentrum für Innere Medizin
Mutlangen, 73557, Germany
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Klinikum der Universität München, Medizinische Klinik und Poliklinik III
München, 83177, Germany
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Studiengesellschaft Onkologie Bielefeld GbR
Bielefeld, 33604, Germany
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Universitätsklinikum Halle, Klinik für Innere Medizin IV
Halle, 06120, Germany
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Universitätsklinikum Münster, Med. Klinik A
Münster, 48149, Germany
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Universitätsklinikum Ulm; Klinik für Innere Medizin Innere Medizin III
Ulm, 89081, Germany
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Universtätsmedizin Mannheim, III. Medizinische Klinik Studienzentrale im MCC
Mannheim, 68167, Germany
Conditions
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