Cheaper antibiotic could fight superbug typhoid
NCT ID NCT07314281
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two antibiotics, azithromycin and meropenem, given through a vein to treat extensively drug-resistant enteric fever (a severe typhoid infection). Researchers will enroll 40 patients aged 1 to 70 years to see which drug clears the infection faster and reduces fever. The goal is to find a more affordable and effective treatment option.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- azithromycin
- What this could lead to
- If azithromycin works, it could offer a cheaper, effective treatment for drug-resistant enteric fever, reducing reliance on meropenem.
- What could go wrong
- This is a small pilot study with only 40 participants, so results may not apply broadly. Azithromycin may not clear the infection as effectively as meropenem.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Indus Hospital & Health Network - Mian Campus
RECRUITINGKarachi, Sindh, Pakistan