Cheaper antibiotic could fight superbug typhoid

NCT ID NCT07314281

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two antibiotics, azithromycin and meropenem, given through a vein to treat extensively drug-resistant enteric fever (a severe typhoid infection). Researchers will enroll 40 patients aged 1 to 70 years to see which drug clears the infection faster and reduces fever. The goal is to find a more affordable and effective treatment option.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

azithromycin

What this could lead to

If azithromycin works, it could offer a cheaper, effective treatment for drug-resistant enteric fever, reducing reliance on meropenem.

What could go wrong

This is a small pilot study with only 40 participants, so results may not apply broadly. Azithromycin may not clear the infection as effectively as meropenem.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

typhoid fever

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Indus Hospital & Health Network - Mian Campus

    RECRUITING

    Karachi, Sindh, Pakistan

    Contact Phone: •••-•••-•••• Email: •••••@•••••